[Epicardial fat Tissue Volumetry: Comparison of Semi-Automatic Measurement and the Machine Learning Algorithm].

Journal: Kardiologiia
Published Date:

Abstract

Aim        To compare assessments of epicardial adipose tissue (EAT) volumes obtained with a semi-automatic, physician-performed analysis and an automatic analysis using a machine-learning algorithm by data of low-dose (LDCT) and standard computed tomography (CT) of chest organs.Material and methods        This analytical, retrospective, transversal study randomly included 100 patients from a database of a united radiological informational service (URIS). The patients underwent LDCT as a part of the project "Low-dose chest computed tomography as a screening method for detection of lung cancer and other diseases of chest organs" (n=50) and chest CT according to a standard protocol (n=50) in outpatient clinics of Moscow. Each image was read by two radiologists on a Syngo. via VB20 workstation. In addition, each image was evaluated with a developed machine-learning algorithm, which provides a completely automatic measurement of EAT.Results   Comparison of EAT volumes obtained with chest LDCT and CT showed highly consistent results both for the expert-performed semi-automatic analyses (correlation coefficient >98 %) and between the expert layout and the machine-learning algorithm (correlation coefficient >95 %). Time of performing segmentation and volumetry on one image with the machine-learning algorithm was not longer than 40 sec, which was 30 times faster than the quantitative analysis performed by an expert and potentially facilitated quantification of the EAT volume in the clinical conditions.Conclusion            The proposed method of automatic volumetry will expedite the analysis of EAT for predicting the risk of ischemic heart disease.

Authors

  • V Y Chernina
    Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department, Moscow.
  • M E Pisov
    Skolkovo Institute of Science and Technology, Moscow.
  • M G Belyaev
    Skolkovo Institute of Science and Technology, Moscow.
  • I V Bekk
    National Medical and Surgical Center named after N.I. Pirogov of the Ministry of Healthcare of the Russian Federation, Moscow.
  • K A Zamyatina
    A.V. Vishnevsky National Medical Research Center of Surgery, Moscow.
  • T A Korb
    Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department, Moscow.
  • O O Aleshina
    Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department, Moscow.
  • E A Shukina
    Moscow State University of Medicine and Dentistry named after A.I. Evdokimov, Moscow.
  • A V Solovev
    Sklifosovsky Clinical and Research Institute for Emergency Medicine, Moscow.
  • R A Skvortsov
    National Medical and Surgical Center named after N.I. Pirogov of the Ministry of Healthcare of the Russian Federation, Moscow.
  • D A Filatova
    Lomonosov Moscow State University, Moscow.
  • D I Sitdikov
    The First Sechenov Moscow State Medical University, Moscow.
  • A O Chesnokova
    The First Sechenov Moscow State Medical University, Moscow.
  • S P Morozov
    Research and Practical Clinical Center of Diagnostics and Telemedicine Technologies, Department of Health Care of Moscow, Moscow, Russia.
  • V A Gombolevsky
    Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department, Moscow.