AIMC Topic: Adipose Tissue

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A dual self-attentive transformer U-Net model for precise pancreatic segmentation and fat fraction estimation.

BMC medical imaging
Accurately segmenting the pancreas from abdominal computed tomography (CT) images is crucial for detecting and managing pancreatic diseases, such as diabetes and tumors. Type 2 diabetes and metabolic syndrome are associated with pancreatic fat accumu...

AI-Driven segmentation and morphogeometric profiling of epicardial adipose tissue in type 2 diabetes.

Cardiovascular diabetology
BACKGROUND: Epicardial adipose tissue (EAT) is associated with cardiometabolic risk in type 2 diabetes (T2D), but its spatial distribution and structural alterations remain understudied. We aim to develop a shape-aware, AI-based method for automated ...

Deep learning models for deriving optimised measures of fat and muscle mass from MRI.

Scientific reports
Fat and muscle mass are potential biomarkers of wellbeing and disease in oncology, but clinical measurement methods vary considerably. Here we evaluate the accuracy, precision and ability to track change for multiple deep learning (DL) models that qu...

Poincare guided geometric UNet for left atrial epicardial adipose tissue segmentation in Dixon MRI images.

Scientific reports
Epicardial Adipose Tissue (EAT) is a recognized risk factor for cardiovascular diseases and plays a pivotal role in the pathophysiology of Atrial Fibrillation (AF). Accurate automatic segmentation of the EAT around the Left Atrium (LA) from Magnetic ...

Gender difference in cross-sectional area and fat infiltration of thigh muscles in the elderly population on MRI: an AI-based analysis.

European radiology experimental
BACKGROUND: Aging alters musculoskeletal structure and function, affecting muscle mass, composition, and strength, increasing the risk of falls and loss of independence in older adults. This study assessed cross-sectional area (CSA) and fat infiltrat...

Epicardial adipose tissue, myocardial remodelling and adverse outcomes in asymptomatic aortic stenosis: a post hoc analysis of a randomised controlled trial.

Heart (British Cardiac Society)
BACKGROUND: Epicardial adipose tissue represents a metabolically active visceral fat depot that is in direct contact with the left ventricular myocardium. While it is associated with coronary artery disease, little is known regarding its role in aort...

Lipidomic profiling of human adiposomes identifies specific lipid shifts linked to obesity and cardiometabolic risk.

JCI insight
BACKGROUNDObesity, a growing health concern, often leads to metabolic disturbances, systemic inflammation, and vascular dysfunction. Emerging evidence suggests that adipose tissue-derived extracellular vesicles (adiposomes) may propagate obesity-rela...

Evaluation of semi-automated versus fully automated technologies for computed tomography scalable body composition analyses in patients with severe acute respiratory syndrome Coronavirus-2.

Clinical nutrition ESPEN
RATIONALE AND OBJECTIVES: Fully automated, artificial intelligence (AI) -based software has recently become available for scalable body composition analysis. Prior to broad application in the clinical arena, validation studies are needed. Our goal wa...

Impact of CT reconstruction algorithms on pericoronary and epicardial adipose tissue attenuation.

European journal of radiology
OBJECTIVE: This study aims to investigate the impact of adaptive statistical iterative reconstruction-Veo (ASIR-V) and deep learning image reconstruction (DLIR) algorithms on the quantification of pericoronary adipose tissue (PCAT) and epicardial adi...

Molecular features and diagnostic modeling of synovium- and IPFP-derived OA macrophages in the inflammatory microenvironment via scRNA-seq and machine learning.

Journal of orthopaedic surgery and research
BACKGROUND: Osteoarthritis (OA) is the leading cause of degenerative joint disease, with total joint replacement as the only definitive cure. However, no disease-modifying therapy is currently available. Inflammation and fibrosis in the infrapatellar...