GODoc: high-throughput protein function prediction using novel k-nearest-neighbor and voting algorithms.
Journal:
BMC bioinformatics
Published Date:
Nov 18, 2020
Abstract
BACKGROUND: Biological data has grown explosively with the advance of next-generation sequencing. However, annotating protein function with wet lab experiments is time-consuming. Fortunately, computational function prediction can help wet labs formulate biological hypotheses and prioritize experiments. Gene Ontology (GO) is a framework for unifying the representation of protein function in a hierarchical tree composed of GO terms.