Joint Imaging Platform for Federated Clinical Data Analytics.

Journal: JCO clinical cancer informatics
Published Date: Nov 1, 2020

Abstract

PURPOSE: Image analysis is one of the most promising applications of artificial intelligence (AI) in health care, potentially improving prediction, diagnosis, and treatment of diseases. Although scientific advances in this area critically depend on the accessibility of large-volume and high-quality data, sharing data between institutions faces various ethical and legal constraints as well as organizational and technical obstacles.

Authors

  • Jonas Scherer
    Division of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany.
  • Marco Nolden
    Medical Imaging Components, Division Medical Image Computing, DKFZ Heidelberg, Germany.
  • Jens Kleesiek
    AG Computational Radiology, Abteilung Radiologie, Deutsches Krebsforschungszentrum (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Deutschland. j.kleesiek@dkfz-heidelberg.de.
  • Jasmin Metzger
    German Cancer Research Center (DKFZ), Medical Image Computing, Heidelberg, Germany.
  • Klaus Kades
    Division of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany.
  • Verena Schneider
    German Cancer Consortium, Heidelberg, Germany.
  • Michael Bach
    Clinic of Radiology and Nuclear Medicine, University Hospital Basel, Petersgraben 4, 4031, Basel, Switzerland.
  • Oliver Sedlaczek
    German Cancer Consortium, Heidelberg, Germany.
  • Andreas M Bucher
    Institute for Diagnostic and Interventional Radiology, University Hospital, Goethe University Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.
  • Thomas J Vogl
    Institute for Diagnostic and Interventional Radiology, University Hospital, Goethe University Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.
  • Frank Grünwald
    German Cancer Consortium, Heidelberg, Germany.
  • Jens-Peter Kühn
    Faculty of Medicine and University Hospital Carl Gustav Carus Dresden, Technische Universität Dresden, Institute and Polyclinic for Diagnostic and Interventional Radiology, Dresden, Germany.
  • Ralf-Thorsten Hoffmann
    Faculty of Medicine and University Hospital Carl Gustav Carus Dresden, Technische Universität Dresden, Institute and Polyclinic for Diagnostic and Interventional Radiology, Dresden, Germany.
  • Jörg Kotzerke
    German Cancer Consortium, Heidelberg, Germany.
  • Oliver Bethge
    German Cancer Consortium, Heidelberg, Germany.
  • Lars Schimmöller
    University Dusseldorf, Medical Faculty, Department of Diagnostic and Interventional Radiology, Dusseldorf, Germany.
  • Gerald Antoch
    University Dusseldorf, Medical Faculty, Department of Diagnostic and Interventional Radiology, Germany.
  • Hans-Wilhelm Müller
    German Cancer Consortium, Heidelberg, Germany.
  • Andreas Daul
    German Cancer Consortium, Heidelberg, Germany.
  • Konstantin Nikolaou
    Department of Diagnostic and Interventional Radiology, Eberhard-Karls-University, Hoppe-Seyler-Str.3, 72076 Tübingen, Germany.
  • Christian la Fougère
    Department of Radiology, Nuclear Medicine, Eberhard Karls University Tübingen, Germany.
  • Wolfgang G Kunz
    Institute for Clinical Radiology, Ludwig-Maximilians-University Hospital, Munich, Germany.
  • Michael Ingrisch
    Department of Radiology, Ludwig-Maximilians-University Munich, Munich, Germany.
  • Balthasar Schachtner
    German Cancer Consortium, Heidelberg, Germany.
  • Jens Ricke
    Department of Radiology, University Hospital Munich, Germany. Electronic address: jens.ricke@med.uni-muenchen.de.
  • Peter Bartenstein
    German Cancer Consortium, Heidelberg, Germany.
  • Felix Nensa
    Institute for AI in Medicine (IKIM), University Hospital Essen, 45131 Essen, Germany.
  • Alexander Radbruch
    Department of Neuroradiology, Heidelberg University Hospital, Heidelberg, Germany; Department of Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Lale Umutlu
    Institute of Diagnostic and Interventional Radiology and Neuroradiology, Departments of.
  • Michael Forsting
    Department of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Hufelandstraße 55, 45147, Essen, Germany.
  • Robert Seifert
    Department of Nuclear Medicine, Medical Faculty, University Hospital Essen, Essen, Deutschland.
  • Ken Herrmann
    Department of Nuclear Medicine, Universitätsklinikum Essen, Essen, Germany.
  • Philipp Mayer
    German Cancer Consortium, Heidelberg, Germany.
  • Hans-Ulrich Kauczor
    Department of Diagnostic and Interventional Radiology, Heidelberg University Hospital, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany.
  • Tobias Penzkofer
    Department of Radiology, Brigham and Women's Hospital, Boston, Massachusetts, USA.
  • Bernd Hamm
    Department of Diagnostic and Interventional Radiology, Charité -Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
  • Winfried Brenner
    German Cancer Consortium, Heidelberg, Germany.
  • Roman Kloeckner
    Department of Diagnostic and Interventional Radiology, University Medical Center of the Johannes Gutenberg University Mainz, Germany.
  • Christoph Düber
    Department of Diagnostic and Interventional Radiology, University Medical Center of the Johannes Gutenberg University Mainz, Germany.
  • Mathias Schreckenberger
    German Cancer Consortium, Heidelberg, Germany.
  • Rickmer Braren
    Department of Diagnostic and Interventional Radiology, School of Medicine, Technical University of Munich, Munich, Germany.
  • Georgios Kaissis
    Department of Diagnostic and Interventional Radiology, School of Medicine, Technical University of Munich, Munich, Germany.
  • Marcus Makowski
    German Cancer Consortium, Heidelberg, Germany.
  • Matthias Eiber
    Department of Urology, Technical University of Munich, Rechts der Isar Medical Center, Munich, Germany.
  • Andrei Gafita
    Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
  • Rupert Trager
    German Cancer Consortium, Heidelberg, Germany.
  • Wolfgang A Weber
    German Cancer Consortium, Heidelberg, Germany.
  • Jakob Neubauer
    German Cancer Consortium, Heidelberg, Germany.
  • Marco Reisert
    Medical Physics, Department of Diagnostic and Interventional Radiology, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Michael Bock
    Department of Radiology, Medical Physics, Medical Center University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Fabian Bamberg
    Department of Diagnostic and Interventional Radiology, University Medical Center Tübingen, Tübingen, Germany.
  • Jürgen Hennig
    German Cancer Consortium, Heidelberg, Germany.
  • Philipp Tobias Meyer
    German Cancer Consortium, Heidelberg, Germany.
  • Juri Ruf
    Department of Nuclear Medicine, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Uwe Haberkorn
    Department of Nuclear Medicine, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.
  • Stefan O Schoenberg
    University Medical Center Mannheim, Faculty of Medicine Mannheim, Institute of Clinical Radiology and Nuclear Medicine, Heidelberg University, Mannheim, Germany.
  • Tristan Kuder
    German Cancer Consortium, Heidelberg, Germany.
  • Peter Neher
    Division of Medical Image Computing (MIC), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 581, 69120 Heidelberg, Germany. Electronic address: p.neher@dkfz.de.
  • Ralf Floca
    Division of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany.
  • Heinz-Peter Schlemmer
    From the Department of Radiology (D.B., P.S., J.P.R., P.K., K.Y., M.F., H.P.S.), Division of Medical Image Computing (S.K., M.G., N.G., K.H.M.H.), Division of Statistics (M.W.), and Department of Medical Physics (T.A.K., F.D.), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg 69120, Germany; German Cancer Consortium (DKTK), Heidelberg, Germany (D.B., H.P.S., K.H.M.H.); and Departments of Urology (J.P.R., B.H., M.H., B.A.H.) and Neuroradiology (P.K.), University of Heidelberg Medical Center, Heidelberg, Germany.
  • Klaus Maier-Hein
    Medical Image Analysis, Division Medical Image Computing, DKFZ Heidelberg, Germany.

Keywords

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