Topology-guided cyclic brain connectivity generation using geometric deep learning.

Journal: Journal of neuroscience methods
Published Date:

Abstract

BACKGROUND: There is a growing need for analyzing medical data such as brain connectomes. However, the unavailability of large-scale training samples increases risks of model over-fitting. Recently, deep learning (DL) architectures quickly gained momentum in synthesizing medical data. However, such frameworks are primarily designed for Euclidean data (e.g., images), overlooking geometric data (e.g., brain connectomes). A few existing geometric DL works that aimed to predict a target brain connectome from a source one primarily focused on domain alignment and were agnostic to preserving the connectome topology.

Authors

  • Abubakhari Sserwadda
    BASIRA Lab, Faculty of Computer and Informatics, Istanbul Technical University, Istanbul, Turkey.
  • Islem Rekik
    Department of Radiology and BRIC, University of North Carolina at Chapel Hill, Chapel Hill, USA.