The Future Directions of Research in Cardiac Anesthesiology.

Journal: Advances in anesthesia
Published Date:

Abstract

This article provides an overview of knowledge gaps that need to be addressed in cardiac anesthesia, including mitigating the inflammatory effects of cardiopulmonary bypass, defining myocardial infarction after cardiac surgery, improving perioperative neurologic outcomes, and the optimal management of patients undergoing valve replacement. In addition, emerging approaches to research conduct are discussed, including the use of new analytical techniques like machine learning, pragmatic trials, and adaptive designs.

Authors

  • Jessica Spence
    Departments of Anesthesia and Critical Care and Health Research Methods, Evaluation, and Impact, McMaster University, HSC 2V9 - 1280 Main Street West, Hamilton, ON L8S 4K1, Canada; Population Health Research Institute (PHRI), C3-7B David Braley Cardiac, Vascular and Stroke Research Institute (DBCVSRI), 237 Barton Street East, Hamilton, ON L8L 2X2, Canada.
  • C David Mazer
    Department of Anesthesia, Li Ka Shing Knowledge Institute of St. Michael's Hospital, 30 Bond Street, Toronto, ON M5B 1W8, Canada; Departments of Anesthesia and Physiology, University of Toronto, Toronto, ON, Canada. Electronic address: david.mazer@unityhealth.to.