Smartwatch Electrocardiogram and Artificial Intelligence for Assessing Cardiac-Rhythm Safety of Drug Therapy in the COVID-19 Pandemic. The QT-logs study.

Journal: International journal of cardiology
PMID: 33524462

Abstract

BACKGROUND: QTc interval monitoring, for the prevention of drug-induced arrhythmias is necessary, especially in the context of coronavirus disease 2019 (COVID-19). For the provision of widespread use, surrogates for 12‑lead ECG QTc assessment may be useful. This prospective observational study compared QTc duration assessed by artificial intelligence (AI-QTc) (Cardiologs®, Paris, France) on smartwatch single‑lead electrocardiograms (SW-ECGs) with those measured on 12‑lead ECGs, in patients with early stage COVID-19 treated with a hydroxychloroquine-azithromycin regimen.

Authors

  • Baptiste Maille
    Assistance Publique - Hôpitaux de Marseille, Centre Hospitalier Universitaire La Timone, Service de Cardiologie, Marseille, France; Aix Marseille University, C2VN, Marseille, France.
  • Marie Wilkin
    Assistance Publique - Hôpitaux de Marseille, Centre Hospitalier Universitaire La Timone, Service de Cardiologie, Marseille, France; Aix Marseille University, C2VN, Marseille, France.
  • Matthieu Million
    IHU-Méditerranée Infection, Marseille, France; Aix-Marseille University, IRD, APHM, MEPHI, Marseille, France.
  • Noémie Rességuier
    Department of Epidemiology and Health Economics, APHM, Marseille, France.
  • Frédéric Franceschi
    Assistance Publique - Hôpitaux de Marseille, Centre Hospitalier Universitaire La Timone, Service de Cardiologie, Marseille, France; Aix Marseille University, C2VN, Marseille, France.
  • Linda Koutbi-Franceschi
    Assistance Publique - Hôpitaux de Marseille, Centre Hospitalier Universitaire La Timone, Service de Cardiologie, Marseille, France; Aix Marseille University, C2VN, Marseille, France.
  • Jérôme Hourdain
    Assistance Publique - Hôpitaux de Marseille, Centre Hospitalier Universitaire La Timone, Service de Cardiologie, Marseille, France; Aix Marseille University, C2VN, Marseille, France.
  • Elisa Martinez
    Assistance Publique - Hôpitaux de Marseille, Centre Hospitalier Universitaire La Timone, Service de Cardiologie, Marseille, France; Aix Marseille University, C2VN, Marseille, France.
  • Maxime Zabern
    Assistance Publique - Hôpitaux de Marseille, Centre Hospitalier Universitaire La Timone, Service de Cardiologie, Marseille, France; Aix Marseille University, C2VN, Marseille, France.
  • Christophe Gardella
    Cardiologs Technologies, Paris, France.
  • Hervé Tissot-Dupont
    IHU-Méditerranée Infection, Marseille, France; Aix-Marseille University, IRD, APHM, MEPHI, Marseille, France.
  • Jagmeet P Singh
    Division of Cardiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
  • Jean-Claude Deharo
    Assistance Publique - Hôpitaux de Marseille, Centre Hospitalier Universitaire La Timone, Service de Cardiologie, Marseille, France; Aix Marseille University, C2VN, Marseille, France. Electronic address: jean-claude.deharo@ap-hm.fr.
  • Laurent Fiorina
    Institut Cardiovasculaire Paris-Sud, Hôpital Privé Jacques Cartier, Ramsay, Massy, France.

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