Prediction of 3D Cardiovascular hemodynamics before and after coronary artery bypass surgery via deep learning.

Journal: Communications biology
Published Date:

Abstract

The clinical treatment planning of coronary heart disease requires hemodynamic parameters to provide proper guidance. Computational fluid dynamics (CFD) is gradually used in the simulation of cardiovascular hemodynamics. However, for the patient-specific model, the complex operation and high computational cost of CFD hinder its clinical application. To deal with these problems, we develop cardiovascular hemodynamic point datasets and a dual sampling channel deep learning network, which can analyze and reproduce the relationship between the cardiovascular geometry and internal hemodynamics. The statistical analysis shows that the hemodynamic prediction results of deep learning are in agreement with the conventional CFD method, but the calculation time is reduced 600-fold. In terms of over 2 million nodes, prediction accuracy of around 90%, computational efficiency to predict cardiovascular hemodynamics within 1 second, and universality for evaluating complex arterial system, our deep learning method can meet the needs of most situations.

Authors

  • Gaoyang Li
    Graduate School of Biomedical Engineering, Tohoku University, Sendai 9808577, Japan.
  • Haoran Wang
    Department of Urology, The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510700, China.
  • Mingzi Zhang
    Institute of Fluid Science, Tohoku University, 2-1-1, Katahira, Aoba-ku, Sendai, Miyagi, 980-8577, Japan.
  • Simon Tupin
    Institute of Fluid Science, Tohoku University, 2-1-1, Katahira, Aoba-ku, Sendai, Miyagi, 980-8577, Japan.
  • Aike Qiao
    College of Life Science and Bioengineering, Beijing University of Technology, Beijing 100124, P.R.China.qak@bjut.edu.cn.
  • Youjun Liu
    College of Life Science and Bio-Engineering, Beijing University of Technology, No. 100 Pingleyuan, Chaoyang District, Beijing 100124, China. Electronic address: lyjlma@bjut.edu.cn.
  • Makoto Ohta
    Graduate School of Biomedical Engineering, Tohoku University, 6-6 Aramaki-aza-aoba, Aoba-ku, Sendai, Miyagi, 980-8579, Japan. makoto.ohta@tohoku.ac.jp.
  • Hitomi Anzai
    Graduate School of Biomedical Engineering, Tohoku University, 6-6 Aramaki-aza-aoba, Aoba-ku, Sendai, Miyagi, 980-8579, Japan.