Body Mass Index Variable Interpolation to Expand the Utility of Real-world Administrative Healthcare Claims Database Analyses.

Journal: Advances in therapy
Published Date:

Abstract

INTRODUCTION: Administrative claims data provide an important source for real-world evidence (RWE) generation, but incomplete reporting, such as for body mass index (BMI), limits the sample sizes that can be analyzed to address certain research questions. The objective of this study was to construct models by implementing machine-learning (ML) algorithms to predict BMI classifications (≥ 30, ≥ 35, and ≥ 40 kg/m) in administrative healthcare claims databases, and then internally and externally validate them.

Authors

  • Bingcao Wu
    Janssen Scientific Affairs, LLC, Titusville, NJ, USA. bwu34@its.jnj.com.
  • Wing Chow
    Janssen Scientific Affairs, LLC, Titusville, NJ, USA.
  • Monish Sakthivel
    Mu Sigma Business Solutions, LLC, Bengaluru, India.
  • Onkar Kakade
    Mu Sigma Business Solutions, LLC, Bengaluru, India.
  • Kartikeya Gupta
    Mu Sigma Business Solutions, LLC, Bengaluru, India.
  • Debra Israel
    Janssen Scientific Affairs, LLC, Titusville, NJ, USA.
  • Yen-Wen Chen
    Janssen Scientific Affairs, LLC, Titusville, NJ, USA.
  • Aarti Susan Kuruvilla
    Mu Sigma Business Solutions, LLC, Bengaluru, India.