Over-fitting suppression training strategies for deep learning-based atrial fibrillation detection.

Journal: Medical & biological engineering & computing
Published Date:

Abstract

Nowadays, deep learning-based models have been widely developed for atrial fibrillation (AF) detection in electrocardiogram (ECG) signals. However, owing to the inevitable over-fitting problem, classification accuracy of the developed models severely differed when applying on the independent test datasets. This situation is more significant for AF detection from dynamic ECGs. In this study, we explored two potential training strategies to address the over-fitting problem in AF detection. The first one is to use the Fast Fourier transform (FFT) and Hanning-window-based filter to suppress the influence from individual difference. Another is to train the model on the wearable ECG data to improve the robustness of model. Wearable ECG data from 29 patients with arrhythmia were collected for at least 24 h. To verify the effectiveness of the training strategies, a Long Short-Term Memory (LSTM) and Convolution Neural Network (CNN)-based model was proposed and tested. We tested the model on the independent wearable ECG data set, as well as the MIT-BIH Atrial Fibrillation database and PhysioNet/Computing in Cardiology Challenge 2017 database. The model achieved 96.23%, 95.44%, and 95.28% accuracy rates on the three databases, respectively. Pertaining to the comparison of the accuracy rates on each training set, the accuracy of the model trained in conjunction with the proposed training strategies only reduced by 2%, while the accuracy of the model trained without the training strategies decreased by approximately 15%. Therefore, the proposed training strategies serve as effective mechanisms for devising a robust AF detector and significantly enhanced the detection accuracy rates of the resulting deep networks.

Authors

  • Xiangyu Zhang
    Department of Geriatrics, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
  • Jianqing Li
    School of Instrument Science and Engineering, Southeast University, Sipailou 2, Nanjing 210096, China.
  • Zhipeng Cai
    The School of Instrument Science and Engineering, Southeast University, Nanjing, China.
  • Li Zhang
    Department of Animal Nutrition and Feed Science, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.
  • Zhenghua Chen
  • Chengyu Liu
    Department of General Surgery, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.