International external validation of the SORG machine learning algorithms for predicting 90-day and one-year survival of patients with spine metastases using a Taiwanese cohort.

Journal: The spine journal : official journal of the North American Spine Society
Published Date: Feb 2, 2021

Abstract

BACKGROUND CONTEXT: Accurately predicting the survival of patients with spinal metastases is important for guiding surgical intervention. The SORG machine-learning (ML) algorithm for the 90-day and one-year mortality of patients with metastatic cancer to the spine has been multiply validated, with a high degree of accuracy in both internal and external validation studies. However, prior external validations were conducted using patient groups located on the east coast of the United States, representing a generally homogeneous population. The aim of this study was to externally validate the SORG algorithms with a Taiwanese population.

Authors

  • Jiun-Jen Yang
    Department of Orthopedics, National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei, Taiwan; School of Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.
  • Chih-Wei Chen
    Graduate Institute of Biomedical Informatics, College of Medical Science and Technology, Taipei Medical University, Taiwan.
  • Mitchell S Fourman
    Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, MA, USA.
  • Michiel E R Bongers
    Department of Orthopedic Surgery, Massachusetts General Hospital, Harvard Medical School, 55 Fruit St, Boston, MA 02114, USA.
  • Aditya V Karhade
    Computational Neurosciences Outcomes Center, Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
  • Olivier Q Groot
    Department of Orthopedic Surgery, Massachusetts General Hospital, Harvard Medical School, 55 Fruit St, Boston, MA 02114, USA.
  • Wei-Hsin Lin
    Department of Orthopedics, National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei, Taiwan.
  • Hung-Kuan Yen
    School of Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.
  • Po-Hao Huang
    Department of Orthopedics, National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei, Taiwan.
  • Shu-Hua Yang
    Department of Orthopedics, National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei, Taiwan.
  • Joseph H Schwab
    Department of Orthopedic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA. Electronic address: jhschwab@mgh.harvard.edu.
  • Ming-Hsiao Hu
    Department of Orthopedics, National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei, Taiwan. Electronic address: minghsiaohu@yahoo.com.tw.

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