Rethinking PICO in the Machine Learning Era: ML-PICO.

Journal: Applied clinical informatics
Published Date:

Abstract

BACKGROUND: Machine learning (ML) has captured the attention of many clinicians who may not have formal training in this area but are otherwise increasingly exposed to ML literature that may be relevant to their clinical specialties. ML papers that follow an outcomes-based research format can be assessed using clinical research appraisal frameworks such as PICO (Population, Intervention, Comparison, Outcome). However, the PICO frameworks strain when applied to ML papers that create new ML models, which are akin to diagnostic tests. There is a need for a new framework to help assess such papers.

Authors

  • Xinran Liu
  • James Anstey
    Intensive Care Unit, Royal Melbourne Hospital, Melbourne, VIC, Australia.
  • Ron Li
    Division of Hospital Medicine, Stanford University, Stanford, California, United States.
  • Chethan Sarabu
    doc.ai, Palo Alto, California, United States.
  • Reiri Sono
    University of California, San Francisco, San Francisco, California, United States.
  • Atul J Butte
    Bakar Computational Health Sciences Institute, University of California San Francisco, San Francisco, CA.