Convolutional neural networks for PET functional volume fully automatic segmentation: development and validation in a multi-center setting.

Journal: European journal of nuclear medicine and molecular imaging
Published Date:

Abstract

PURPOSE: In this work, we addressed fully automatic determination of tumor functional uptake from positron emission tomography (PET) images without relying on other image modalities or additional prior constraints, in the context of multicenter images with heterogeneous characteristics.

Authors

  • Andrei Iantsen
    LaTIM, INSERM, UMR 1101, University Brest, Brest, France. andrei.iantsen@inserm.fr.
  • Marta Ferreira
    GIGA-CRC in vivo Imaging, University of Liège, Liège, Belgium.
  • Francois Lucia
    LaTIM, INSERM, UMR 1101, University of Brest, CHRU Brest, France.
  • Vincent Jaouen
    LaTIM, INSERM UMR 1101, IBRBS, Faculty of Medicine, Univ Brest, 22 avenue Camille Desmoulins, 29238, Brest, France.
  • Caroline Reinhold
    Department of Radiology, McGill University Health Center, Montréal, Québec, Canada.
  • Pietro Bonaffini
    Department of Radiology, McGill University Health Centre (MUHC), Montreal, Canada.
  • Joanne Alfieri
    Department of Radiation Oncology, McGill University Health Centre, Montreal, Quebec.
  • Ramon Rovira
    Gynecology Oncology and Laparoscopy Department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
  • Ingrid Masson
    INSERM, UMR 1101, LaTIM, University of Brest, Brest, France.
  • Philippe Robin
    Nuclear Medicine Department, University Hospital, Brest, France.
  • Augustin Mervoyer
    Department of Radiation Oncology, Institut de cancérologie de l'Ouest René-Gauducheau, Saint-Herblain, France.
  • Caroline Rousseau
  • Frédéric Kridelka
    Division of Oncological Gynecology, University Hospital of Liège, Liège, Belgium.
  • Marjolein Decuypere
    Division of Oncological Gynecology, University Hospital of Liège, Liège, Belgium.
  • Pierre Lovinfosse
    Nuclear Medicine and Oncological Imaging, Department of Medical Physics, CHU of Liège, Liège, Belgium.
  • Olivier Pradier
    LaTIM, INSERM, UMR 1101, Brest 29609, France and Radiotherapy Department, CHRU Morvan, Brest 29609, France.
  • Roland Hustinx
    Nuclear Medicine Department, Centre Hospitalier Universitaire de Liège, Liège, Belgium.
  • Ulrike Schick
    The Royal Marsden NHS Foundation Trust, London, UK.
  • Dimitris Visvikis
    LaTIM, INSERM, UMR 1101, Brest 29609, France.
  • Mathieu Hatt
    LaTIM, INSERM, UMR 1101, Brest 29609, France.