AIMC Topic: Positron-Emission Tomography
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A novel neuroimaging based early detection framework for alzheimer disease using deep learning.
Scientific reports
Jul 2, 2025
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that significantly impacts cognitive function, posing a major global health challenge. Despite its rising prevalence, particularly in low and middle-income countries, early diagnosi...
Machine learning model for predicting Amyloid-β positivity and cognitive status using early-phase F-Florbetaben PET and clinical features.
Scientific reports
Jul 1, 2025
This study developed machine learning models to predict Aβ positivity in Alzheimer's disease by integrating early-phase F-Florbetaben PET and clinical data to improve diagnostic accuracy. Furthermore, the study explored machine learning models to pre...
An FDG-PET-Based Machine Learning Framework to Support Neurologic Decision-Making in Alzheimer Disease and Related Disorders.
Neurology
Jun 27, 2025
BACKGROUND AND OBJECTIVES: Distinguishing neurodegenerative diseases is a challenging task requiring neurologic expertise. Clinical decision support systems (CDSSs) powered by machine learning (ML) and artificial intelligence can assist with complex ...
Brain metabolic imaging-based model identifies cognitive stability in prodromal Alzheimer's disease.
Scientific reports
May 17, 2025
The recent approval of anti-amyloid pharmaceuticals for the treatment of Alzheimer's disease (AD) has created a pressing need for the ability to accurately identify optimal candidates for anti-amyloid therapy, specifically those with evidence for inc...
A review of multimodal fusion-based deep learning for Alzheimer's disease.
Neuroscience
Apr 24, 2025
Alzheimer's Disease (AD) as one of the most prevalent neurodegenerative disorders worldwide, characterized by significant memory and cognitive decline in its later stages, severely impacting daily lives. Consequently, early diagnosis and accurate ass...
Utilizing Pix2Pix conditional generative adversarial networks to recover missing data in preclinical PET scanner sinogram gaps.
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
Apr 14, 2025
BACKGROUND: The presence of a gap between adjacent detector blocks in Positron Emission Tomography (PET) scanners introduces a partial loss of projection data, which can degrade the image quality and quantitative accuracy of reconstructed PET images....
Depth-of-interaction encoding techniques for pixelated PET detectors enabled by machine learning methods and fast waveform digitization.
Physics in medicine and biology
Apr 14, 2025
. Pixelated detectors with single-ended readout are routinely used by commercial positron emission tomography scanners owing to their good energy and timing resolution and optimized manufacturing, but they typically do not provide depth-of-interactio...
IT: An interpretable transformer model for Alzheimer's disease prediction based on PET/MR images.
NeuroImage
Apr 11, 2025
Alzheimer's disease (AD) represents a significant challenge due to its progressive neurodegenerative impact, particularly within an aging global demographic. This underscores the critical need for developing sophisticated diagnostic tools for its ear...
Amyloid-β Deposition Prediction With Large Language Model Driven and Task-Oriented Learning of Brain Functional Networks.
IEEE transactions on medical imaging
Apr 3, 2025
Amyloid- positron emission tomography can reflect the Amyloid- protein deposition in the brain and thus serves as one of the golden standards for Alzheimer's disease (AD) diagnosis. However, its practical cost and high radioactivity hinder its applic...
POUR-Net: A Population-Prior-Aided Over-Under-Representation Network for Low-Count PET Attenuation Map Generation.
IEEE transactions on medical imaging
Apr 3, 2025
Low-dose PET offers a valuable means of minimizing radiation exposure in PET imaging. However, the prevalent practice of employing additional CT scans for generating attenuation maps ( -map) for PET attenuation correction significantly elevates radia...
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