Analysis of protein determinants of host-specific infection properties of polyomaviruses using machine learning.

US Health Policy Oncology/Hematology
Journal: Genes & genomics
Published Date: Mar 1, 2021

Abstract

BACKGROUND: The large tumor antigen (LT-Ag) and major capsid protein VP1 are known to play important roles in determining the host-specific infection properties of polyomaviruses (PyVs).

Authors

  • Myeongji Cho
    Laboratory of Computational Virology & Viroinformatics, Graduate School of Public Health, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, Korea.
  • Hayeon Kim
    Department of Biomedical Laboratory Science, Kyungdong University, 815 Gyeonhwon-ro, Munmak, Wonju, Gangwondo, 24695, Korea.
  • Hyeon S Son
    Laboratory of Computational Virology & Viroinformatics, Graduate School of Public Health, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, Korea. [email protected].

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