Machine Learning-Driven Metabolomic Evaluation of Cerebrospinal Fluid: Insights Into Poor Outcomes After Aneurysmal Subarachnoid Hemorrhage.

Journal: Neurosurgery
Published Date: Apr 15, 2021

Abstract

BACKGROUND: Aneurysmal subarachnoid hemorrhage (aSAH) is associated with a high mortality and poor neurologic outcomes. The biologic underpinnings of the morbidity and mortality associated with aSAH remain poorly understood.

Authors

  • Matthew Koch
    Department of Neurosurgery, Massachusetts General Hospital, Boston, Massachusetts.
  • Animesh Acharjee
    College of Medicine and Health, School of Medical Sciences, Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom.
  • Zsuzsanna Ament
    Medical Research Council, Elsie Widdowson Laboratory, 120 Fulbourn Road, Cambridge, CB1 9NL, UK.
  • Riana Schleicher
    Division of Neurocritical Care and Center for Genomic Medicine, Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts.
  • Matthew Bevers
    Divisions of Stroke, Cerebrovascular and Critical Care Neurology, Brigham and Women's Hospital, Boston, Massachusetts.
  • Christopher Stapleton
    Department of Neurosurgery, Massachusetts General Hospital, Boston, Massachusetts.
  • Aman Patel
    Department of Neurosurgery, Massachusetts General Hospital, Boston, Massachusetts.
  • W Taylor Kimberly
    Division of Neurocritical Care and Center for Genomic Medicine, Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts.

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