Machine learning approaches to study glioblastoma: A review of the last decade of applications.

Journal: Cancer reports (Hoboken, N.J.)
PMID:

Abstract

BACKGROUND: Glioblastoma (GB, formally glioblastoma multiforme) is a malignant type of brain cancer that currently has no cure and is characterized by being highly heterogeneous with high rates of re-incidence and therapy resistance. Thus, it is urgent to characterize the mechanisms of GB pathogenesis to help researchers identify novel therapeutic targets to cure this devastating disease. Recently, a promising approach to identifying novel therapeutic targets is the integration of tumor omics data with clinical information using machine learning (ML) techniques.

Authors

  • Jessica Valdebenito
    Programa de Bioestadística, Escuela de Salud Pública, Universidad de Chile, Santiago, Chile.
  • Felipe Medina
    Programa de Bioestadística, Escuela de Salud Pública, Universidad de Chile, Santiago, Chile.