SSMD: Semi-Supervised medical image detection with adaptive consistency and heterogeneous perturbation.

Journal: Medical image analysis
Published Date:

Abstract

Semi-Supervised classification and segmentation methods have been widely investigated in medical image analysis. Both approaches can improve the performance of fully-supervised methods with additional unlabeled data. However, as a fundamental task, semi-supervised object detection has not gained enough attention in the field of medical image analysis. In this paper, we propose a novel Semi-Supervised Medical image Detector (SSMD). The motivation behind SSMD is to provide free yet effective supervision for unlabeled data, by regularizing the predictions at each position to be consistent. To achieve the above idea, we develop a novel adaptive consistency cost function to regularize different components in the predictions. Moreover, we introduce heterogeneous perturbation strategies that work in both feature space and image space, so that the proposed detector is promising to produce powerful image representations and robust predictions. Extensive experimental results show that the proposed SSMD achieves the state-of-the-art performance at a wide range of settings. We also demonstrate the strength of each proposed module with comprehensive ablation studies.

Authors

  • Hong-Yu Zhou
    Department of Respiratory and Critical Care Medicine, National Clinical Research Center for Geriatrics, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu 610041, P.R. China; Department of Computer Science, The University of Hong Kong, Pokfulam, Hong Kong.
  • Chengdi Wang
    Department of Pulmonary and Critical Care Medicine, Med-X Center for Manufacturing, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
  • Haofeng Li
    Shenzhen Research Institute of Big Data, The Chinese University of Hong Kong, Shenzhen 518000, P.R. China.
  • Gang Wang
    National Clinical Research Center for Mental Disorders & Beijing Key Laboratory of Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, China.
  • Shu Zhang
    State University of New York, Department of Radiology, Stony Brook, New York, United States.
  • Weimin Li
    Department of Psychiatry, Sleep Medicine Center, Nanfang Hospital, Southern Medical University, Guangzhou, China.
  • Yizhou Yu
    Department of Computer Science, The University of Hong Kong, Pok Fu Lam, Hong Kong.