Applications of deep learning techniques for automated multiple sclerosis detection using magnetic resonance imaging: A review.

Journal: Computers in biology and medicine
Published Date:

Abstract

Multiple Sclerosis (MS) is a type of brain disease which causes visual, sensory, and motor problems for people with a detrimental effect on the functioning of the nervous system. In order to diagnose MS, multiple screening methods have been proposed so far; among them, magnetic resonance imaging (MRI) has received considerable attention among physicians. MRI modalities provide physicians with fundamental information about the structure and function of the brain, which is crucial for the rapid diagnosis of MS lesions. Diagnosing MS using MRI is time-consuming, tedious, and prone to manual errors. Research on the implementation of computer aided diagnosis system (CADS) based on artificial intelligence (AI) to diagnose MS involves conventional machine learning and deep learning (DL) methods. In conventional machine learning, feature extraction, feature selection, and classification steps are carried out by using trial and error; on the contrary, these steps in DL are based on deep layers whose values are automatically learn. In this paper, a complete review of automated MS diagnosis methods performed using DL techniques with MRI neuroimaging modalities is provided. Initially, the steps involved in various CADS proposed using MRI modalities and DL techniques for MS diagnosis are investigated. The important preprocessing techniques employed in various works are analyzed. Most of the published papers on MS diagnosis using MRI modalities and DL are presented. The most significant challenges facing and future direction of automated diagnosis of MS using MRI modalities and DL techniques are also provided.

Authors

  • Afshin Shoeibi
    Faculty of Electrical Engineering, Biomedical Data Acquisition Lab (BDAL), K. N. Toosi University of Technology, Tehran 1631714191, Iran.
  • Marjane Khodatars
    Mashhad Branch, Islamic Azad University, Mashhad 91735413, Iran.
  • Mahboobeh Jafari
    Electrical and Computer Engineering Faculty, Semnan University, Semnan 3513119111, Iran.
  • Parisa Moridian
    Faculty of Engineering, Science and Research Branch, Islamic Azad University, Tehran 1477893855, Iran.
  • Mitra Rezaei
    Electrical and Computer Engineering Dept., Tarbiat Modares University, Tehran, Iran.
  • Roohallah Alizadehsani
    Institute for Intelligent Systems Research and Innovation (IISRI), Deakin University, Geelong, Australia.
  • Fahime Khozeimeh
    Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
  • Juan Manuel Górriz
    Department of Signal Theory, Networking and Communications, University of Granada, Granada, Spain.
  • Jónathan Heras
    Department of Mathematics and Computer Science, University of La Rioja, La Rioja, Spain.
  • Maryam Panahiazar
    Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN, USA.
  • Saeid Nahavandi
  • U Rajendra Acharya
    School of Business (Information Systems), Faculty of Business, Education, Law & Arts, University of Southern Queensland, Darling Heights, Australia.