BACKGROUND AND OBJECTIVES: Cortical lesions in multiple sclerosis (MS) severely affect cognition, but their longitudinal evolution and impact on specific cognitive functions remain understudied. This study investigates the evolution of function-speci...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
40039786
The goal of the present pilot investigation is to examine the effects of 8 weeks of supervised, over-ground gait training using a robotic exoskeleton (RE) compared with a control condition (conventional gait therapy, CGT) in persons with MS with ambu...
Despite several automated strategies for identification/segmentation of Multiple Sclerosis (MS) lesions in Magnetic Resonance Imaging (MRI) being developed, they consistently fall short when compared to the performance of human experts. This emphasiz...
Artificial intelligence (AI) can play a vital role in achieving a shift towards predictive, preventive, and personalized medicine, provided we are guided by the science with and of patient input. Patient-reported outcome measures (PROMs) represent a ...
Journal of neuroimaging : official journal of the American Society of Neuroimaging
39923192
BACKGROUND AND PURPOSE: Accurate and consistent lesion segmentation from magnetic resonance imaging is required for longitudinal multiple sclerosis (MS) data analysis. In this work, we propose two new transfer learning-based pipelines to improve segm...
International journal of molecular sciences
40076709
Complex diseases pose challenges in prediction due to their multifactorial and polygenic nature. This study employed machine learning (ML) to analyze genomic data from the UK Biobank, aiming to predict the genomic predisposition to complex diseases l...
INTRODUCTION: Multiple sclerosis (MS) is an autoimmune neurodegenerative disease affecting the central nervous system. MS diagnosis is complex, requiring magnetic resonance imaging and cerebrospinal fluid analysis due to the lack of definitive biomar...
Advances in clinical and experimental medicine : official organ Wroclaw Medical University
39945559
BACKGROUND: Lhermitte's sign (LS) is an important clinical marker for patients with multiple sclerosis (MS). Research on pediatric-onset MS (POMS) and LS is limited. To date, there has been no research conducted on the clinical and artificial intelli...
Disorders of the central nervous system, including neurodegenerative diseases, frequently affect the brainstem and can present with focal atrophy. This study aimed to (1) optimize deep learning-based brainstem segmentation for a wide range of patholo...
Background Portable low-field-strength (64-mT) MRI scanners show promise for increasing access to neuroimaging for clinical and research purposes; however, these devices produce lower-quality images than conventional high-field-strength scanners. Pur...