Zoster patients on earth and astronauts in space share similar immunologic profiles.

Journal: Life sciences in space research
PMID: 32414485

Abstract

BACKGROUND: On long-duration spaceflight, most astronauts experience persistent immune dysregulation and the reactivation of latent herpesviruses, including varicella zoster virus (VZV). To understand the clinical risk of these perturbations to astronauts, we paralleled the immunology and virology work-up of astronauts to otherwise healthy terrestrial persons with acute herpes zoster.

Authors

  • Hawley E Kunz
    Mayo Clinic, Rochester, MN, United States.
  • George Makedonas
    JES Tech, Houston, TX, United States. Electronic address: george.makedonas@nasa.gov.
  • Satish K Mehta
    JES Tech, Houston, TX, United States.
  • Stephen K Tyring
    University of Texas Houston Health Sciences Center, Houston, TX, United States.
  • Ramya Vangipuram
    University of Texas Houston Health Sciences Center, Houston, TX, United States.
  • Heather Quiriarte
    Louisiana State University, Baton Rouge, LA, United States.
  • Mayra Nelman-Gonzalez
    KBR, Houston, Texas, United States.
  • Duane L Pierson
    NASA Johnson Space Center, 2101 E NASA Pkwy, Houston, TX 77058, United States.
  • Brian E Crucian
    NASA Johnson Space Center, 2101 E NASA Pkwy, Houston, TX 77058, United States. Electronic address: brian.crucian-1@nasa.gov.

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