Accurate plant pathogen effector protein classification ab initio with deepredeff: an ensemble of convolutional neural networks.
Journal:
BMC bioinformatics
Published Date:
Jul 17, 2021
Abstract
BACKGROUND: Plant pathogens cause billions of dollars of crop loss every year and are a major threat to global food security. Effector proteins are the tools such pathogens use to infect the cell, predicting effectors de novo from sequence is difficult because of the heterogeneity of the sequences. We hypothesised that deep learning classifiers based on Convolutional Neural Networks would be able to identify effectors and deliver new insights.