Detecting lumbar lesions in Tc-MDP SPECT by deep learning: Comparison with physicians.

Journal: Medical physics
Published Date: Jul 11, 2021

Abstract

PURPOSE: Tc-MDP single-photon emission computed tomography (SPECT) is an established tool for diagnosing lumbar stress, a common cause of low back pain (LBP) in pediatric patients. However, detection of small stress lesions is complicated by the low quality of SPECT, leading to significant interreader variability. The study objectives were to develop an approach based on a deep convolutional neural network (CNN) for detecting lumbar lesions in Tc-MDP scans and to compare its performance to that of physicians in a localization receiver operating characteristic (LROC) study.

Authors

  • Yoann Petibon
    Gordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, United States of America.
  • Frederic Fahey
    Department of Radiology, Harvard Medical School, Boston, Massachusetts, USA.
  • Xinhua Cao
    Department of Radiology, Boston Children's Hospital, Boston, MA, USA.
  • Zakhar Levin
    Gordon Center of Medical Imaging, Massachusetts General Hospital, Boston, Massachusetts, USA.
  • Briana Sexton-Stallone
    Division of Nuclear Medicine and Molecular Imaging, Boston Children's Hospital, Boston, Massachusetts, USA.
  • Anthony Falone
    Division of Nuclear Medicine and Molecular Imaging, Boston Children's Hospital, Boston, Massachusetts, USA.
  • Katherine Zukotynski
    Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada; and zukotynk@mcmaster.ca.
  • Neha Kwatra
    Department of Radiology, Harvard Medical School, Boston, Massachusetts, USA.
  • Ruth Lim
    Department of Radiology, Massachusetts General Hospital, Boston, MA, USA.
  • Zvi Bar-Sever
    Institute of Nuclear Medicine, Schneider Children's Medical Center of Israel, Petah Tikva, Israel.
  • Yanis Chemli
    Gordon Center of Medical Imaging, Massachusetts General Hospital, Boston, Massachusetts, USA.
  • S Ted Treves
    Department of Radiology, Harvard Medical School, Boston, Massachusetts, USA.
  • Georges El Fakhri
    Gordon Center of Medical Imaging, Massachusetts General Hospital, Boston, Massachusetts, USA.
  • Jinsong Ouyang
    Gordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, United States of America.

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