SPECT is a widely used imaging modality in nuclear medicine which provides essential functional insights into cardiovascular, neurological, and oncological diseases. However, SPECT imaging suffers from limited quantitative accuracy due to low spatial...
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Apr 1, 2025
We previously demonstrated that a deep learning (DL) model of myocardial perfusion SPECT imaging improved accuracy for detection of obstructive coronary artery disease (CAD). We aimed to improve the clinical translatability of this artificial intelli...
OBJECTIVE: To provide fully automatic scanner-independent 5-level categorization of the [I]FP-CIT uptake in striatal subregions in dopamine transporter SPECT.
European journal of nuclear medicine and molecular imaging
Feb 20, 2025
BACKGROUND: Myocardial perfusion imaging (MPI) using single-photon emission computed tomography (SPECT) is a well-established modality for noninvasive diagnostic assessment of coronary artery disease (CAD). However, the time-consuming and experience-...
OBJECTIVE: Functional imaging using the dopamine transporter (DAT) as a biomarker has proven effective in assessing dopaminergic neuron degeneration in the striatum. In assessing the neuron degeneration, visual and semiquantitative methods are used t...
Medical & biological engineering & computing
Feb 11, 2025
Multi-modality medical image fusion (MMIF) technology utilizes the complementarity of different modalities to provide more comprehensive diagnostic insights for clinical practice. Existing deep learning-based methods often focus on extracting the pri...
BACKGROUND: Computed tomography attenuation correction (CTAC) is commonly used in cardiac SPECT imaging to reduce soft-tissue attenuation artifacts. However, CTAC is prone to inaccuracies due to CT artifacts and SPECT-CT mismatch, along with addition...
European journal of nuclear medicine and molecular imaging
Nov 27, 2024
PURPOSE: Deep convolutional neural networks (CNN) hold promise for assisting the interpretation of dopamine transporter (DAT)-SPECT. For improved communication of uncertainty to the user it is crucial to reliably discriminate certain from inconclusiv...
INTRODUCTION: Attenuation correction (AC) is necessary for accurate assessment of radioactive distribution in single photon emission computed tomography (SPECT). The method of computed tomography-based AC (CTAC) is widely used because of its accuracy...
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
Nov 2, 2024
BACKGROUND: In myocardial perfusion imaging (MPI) with single-photon emission computed tomography (SPECT), ungated studies are used for evaluation of perfusion defects despite motion blur. We investigate the potential benefit of motion correction usi...
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