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Tomography, Emission-Computed, Single-Photon

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Classification of Artifacts in Multimodal Fused Images using Transfer Learning with Convolutional Neural Networks.

Current medical imaging
INTRODUCTION: Multimodal medical image fusion techniques play an important role in clinical diagnosis and treatment planning. The process of combining multimodal images involves several challenges depending on the type of modality, transformation tec...

Development and validation of a machine learning model to predict myocardial blood flow and clinical outcomes from patients' electrocardiograms.

Cell reports. Medicine
We develop a machine learning (ML) model using electrocardiography (ECG) to predict myocardial blood flow reserve (MFR) and assess its prognostic value for major adverse cardiovascular events (MACEs). Using 3,639 ECG-positron emission tomography (PET...

Incorporating label uncertainty during the training of convolutional neural networks improves performance for the discrimination between certain and inconclusive cases in dopamine transporter SPECT.

European journal of nuclear medicine and molecular imaging
PURPOSE: Deep convolutional neural networks (CNN) hold promise for assisting the interpretation of dopamine transporter (DAT)-SPECT. For improved communication of uncertainty to the user it is crucial to reliably discriminate certain from inconclusiv...

Accuracy of deep learning-based attenuation correction in Tc-GSA SPECT/CT hepatic imaging.

Radiography (London, England : 1995)
INTRODUCTION: Attenuation correction (AC) is necessary for accurate assessment of radioactive distribution in single photon emission computed tomography (SPECT). The method of computed tomography-based AC (CTAC) is widely used because of its accuracy...

Cardiac motion correction with a deep learning network for perfusion defect assessment in single-photon emission computed tomography myocardial perfusion imaging.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
BACKGROUND: In myocardial perfusion imaging (MPI) with single-photon emission computed tomography (SPECT), ungated studies are used for evaluation of perfusion defects despite motion blur. We investigate the potential benefit of motion correction usi...

Interpretation of basal nuclei in brain dopamine transporter scans using a deep convolutional neural network.

Nuclear medicine communications
OBJECTIVE: Functional imaging using the dopamine transporter (DAT) as a biomarker has proven effective in assessing dopaminergic neuron degeneration in the striatum. In assessing the neuron degeneration, visual and semiquantitative methods are used t...

Deep learning-based CT-free attenuation correction for cardiac SPECT: a new approach.

BMC medical imaging
BACKGROUND: Computed tomography attenuation correction (CTAC) is commonly used in cardiac SPECT imaging to reduce soft-tissue attenuation artifacts. However, CTAC is prone to inaccuracies due to CT artifacts and SPECT-CT mismatch, along with addition...

Deep learning-based approach for acquisition time reduction in ventilation SPECT in patients after lung transplantation.

Radiological physics and technology
We aimed to evaluate the image quality and diagnostic performance of chronic lung allograft dysfunction (CLAD) with lung ventilation single-photon emission computed tomography (SPECT) images acquired briefly using a convolutional neural network (CNN)...

AI in SPECT Imaging: Opportunities and Challenges.

Seminars in nuclear medicine
SPECT is a widely used imaging modality in nuclear medicine which provides essential functional insights into cardiovascular, neurological, and oncological diseases. However, SPECT imaging suffers from limited quantitative accuracy due to low spatial...

Artificial Intelligence-Enhanced Perfusion Scoring Improves the Diagnostic Accuracy of Myocardial Perfusion Imaging.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine
We previously demonstrated that a deep learning (DL) model of myocardial perfusion SPECT imaging improved accuracy for detection of obstructive coronary artery disease (CAD). We aimed to improve the clinical translatability of this artificial intelli...