. In single-photon emission computed tomography (SPECT) image reconstruction, limited-angle conditions lead to a loss of frequency components, which distort the reconstructed tomographic image along directions corresponding to the non-collected proje...
SPECT is a widely used imaging modality in nuclear medicine which provides essential functional insights into cardiovascular, neurological, and oncological diseases. However, SPECT imaging suffers from limited quantitative accuracy due to low spatial...
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Apr 1, 2025
We previously demonstrated that a deep learning (DL) model of myocardial perfusion SPECT imaging improved accuracy for detection of obstructive coronary artery disease (CAD). We aimed to improve the clinical translatability of this artificial intelli...
OBJECTIVE: To provide fully automatic scanner-independent 5-level categorization of the [I]FP-CIT uptake in striatal subregions in dopamine transporter SPECT.
European journal of nuclear medicine and molecular imaging
Feb 20, 2025
BACKGROUND: Myocardial perfusion imaging (MPI) using single-photon emission computed tomography (SPECT) is a well-established modality for noninvasive diagnostic assessment of coronary artery disease (CAD). However, the time-consuming and experience-...
OBJECTIVE: Functional imaging using the dopamine transporter (DAT) as a biomarker has proven effective in assessing dopaminergic neuron degeneration in the striatum. In assessing the neuron degeneration, visual and semiquantitative methods are used t...
Medical & biological engineering & computing
Feb 11, 2025
Multi-modality medical image fusion (MMIF) technology utilizes the complementarity of different modalities to provide more comprehensive diagnostic insights for clinical practice. Existing deep learning-based methods often focus on extracting the pri...
BACKGROUND: Computed tomography attenuation correction (CTAC) is commonly used in cardiac SPECT imaging to reduce soft-tissue attenuation artifacts. However, CTAC is prone to inaccuracies due to CT artifacts and SPECT-CT mismatch, along with addition...
BACKGROUND: Noninvasive cardiac testing with coronary computed tomography angiography (CCTA) and single-photon emission computed tomography (SPECT) are becoming alternatives to invasive angiography for the evaluation of obstructive coronary artery di...
European journal of nuclear medicine and molecular imaging
Nov 27, 2024
PURPOSE: Deep convolutional neural networks (CNN) hold promise for assisting the interpretation of dopamine transporter (DAT)-SPECT. For improved communication of uncertainty to the user it is crucial to reliably discriminate certain from inconclusiv...
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