Predictive and interpretable models via the stacked elastic net.
Journal:
Bioinformatics (Oxford, England)
Published Date:
Aug 4, 2021
Abstract
MOTIVATION: Machine learning in the biomedical sciences should ideally provide predictive and interpretable models. When predicting outcomes from clinical or molecular features, applied researchers often want to know which features have effects, whether these effects are positive or negative and how strong these effects are. Regression analysis includes this information in the coefficients but typically renders less predictive models than more advanced machine learning techniques.