Minimally invasive thymectomy for myasthenia gravis favours left-sided approach and low severity class.

Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
PMID:

Abstract

OBJECTIVES: Complete thymectomy is a key component of the optimal treatment for myasthenia gravis. Unilateral, minimally invasive approaches are increasingly utilized with debate about the optimal laterality approach. A right-sided approach has a wider field of view, while a left-sided approach accesses potentially more thymic tissue. We aimed to assess the impact of laterality on perioperative and medium-term outcomes, and to identify predictors of a 'good outcome' using standard definitions.

Authors

  • Candice L Wilshire
    Department of Thoracic Surgery, Swedish Cancer Institute, Seattle, WA, USA.
  • Sandra L Blitz
    Department of Thoracic Surgery, Swedish Cancer Institute, Seattle, WA, USA.
  • Carson C Fuller
    Department of Thoracic Surgery, Swedish Cancer Institute, Seattle, WA, USA.
  • Jens C Rückert
    Department of Thoracic Surgery, Charité-Universitätsmedizin Berlin, Berlin, Germany.
  • Feng Li
    Department of General Surgery, Shanghai Traditional Chinese Medicine (TCM)-INTEGRATED Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China.
  • Robert J Cerfolio
    Division of Cardiothoracic Surgery, Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama. Electronic address: rcerfolio@uabmc.edu.
  • Asem F Ghanim
    Department of Thoracic Surgery, University of Alabama at Birmingham, Birmingham, AL, USA.
  • Mark W Onaitis
    Department of Surgery, Division of Cardiovascular and Thoracic Surgery, Duke University Medical Center, Durham, North Carolina.
  • Inderpal S Sarkaria
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Dennis A Wigle
    Department of Thoracic Surgery, Mayo Clinic, Rochester, MN, USA.
  • Vijay Joshi
    Department of Thoracic Surgery, Mayo Clinic, Rochester, MN, USA.
  • Scott Reznik
    Department of Thoracic Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Adam J Bograd
    Department of Thoracic Surgery, Swedish Cancer Institute, Seattle, WA, USA.
  • Eric Vallières
    Department of Thoracic Surgery, Swedish Cancer Institute, Seattle, WA, USA.
  • Brian E Louie
    Division of Thoracic Surgery, Swedish Cancer Institute, Seattle, Washington.