Spliceator: multi-species splice site prediction using convolutional neural networks.

Journal: BMC bioinformatics
Published Date: Nov 23, 2021

Abstract

BACKGROUND: Ab initio prediction of splice sites is an essential step in eukaryotic genome annotation. Recent predictors have exploited Deep Learning algorithms and reliable gene structures from model organisms. However, Deep Learning methods for non-model organisms are lacking.

Authors

  • Nicolas Scalzitti
    Complex Systems and Translational Bioinformatics (CSTB), ICube Laboratory, UMR7357, University of Strasbourg, 1 rue Eugène Boeckel, 67000, Strasbourg, France.
  • Arnaud Kress
    Complex Systems and Translational Bioinformatics (CSTB), ICube Laboratory, UMR7357, University of Strasbourg, 1 rue Eugène Boeckel, 67000, Strasbourg, France.
  • Romain Orhand
    Complex Systems and Translational Bioinformatics (CSTB), ICube Laboratory, UMR7357, University of Strasbourg, 1 rue Eugène Boeckel, 67000, Strasbourg, France.
  • Thomas Weber
    Complex Systems and Translational Bioinformatics (CSTB), ICube Laboratory, UMR7357, University of Strasbourg, 1 rue Eugène Boeckel, 67000, Strasbourg, France.
  • Luc Moulinier
    Complex Systems and Translational Bioinformatics (CSTB), ICube Laboratory, UMR7357, University of Strasbourg, 1 rue Eugène Boeckel, 67000, Strasbourg, France.
  • Anne Jeannin-Girardon
    Complex Systems and Translational Bioinformatics (CSTB), ICube Laboratory, UMR7357, University of Strasbourg, 1 rue Eugène Boeckel, 67000, Strasbourg, France.
  • Pierre Collet
    Complex Systems and Translational Bioinformatics (CSTB), ICube Laboratory, UMR7357, University of Strasbourg, 1 rue Eugène Boeckel, 67000, Strasbourg, France.
  • Olivier Poch
    Complex Systems and Translational Bioinformatics (CSTB), ICube Laboratory, UMR7357, University of Strasbourg, 1 rue Eugène Boeckel, 67000, Strasbourg, France.
  • Julie D Thompson
    Complex Systems and Translational Bioinformatics (CSTB), ICube Laboratory, UMR7357, University of Strasbourg, 1 rue Eugène Boeckel, 67000, Strasbourg, France. thompson@unistra.fr.

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