Machine intelligence in non-invasive endocrine cancer diagnostics.

Journal: Nature reviews. Endocrinology
Published Date:

Abstract

Artificial intelligence (AI) has illuminated a clear path towards an evolving health-care system replete with enhanced precision and computing capabilities. Medical imaging analysis can be strengthened by machine learning as the multidimensional data generated by imaging naturally lends itself to hierarchical classification. In this Review, we describe the role of machine intelligence in image-based endocrine cancer diagnostics. We first provide a brief overview of AI and consider its intuitive incorporation into the clinical workflow. We then discuss how AI can be applied for the characterization of adrenal, pancreatic, pituitary and thyroid masses in order to support clinicians in their diagnostic interpretations. This Review also puts forth a number of key evaluation criteria for machine learning in medicine that physicians can use in their appraisals of these algorithms. We identify mitigation strategies to address ongoing challenges around data availability and model interpretability in the context of endocrine cancer diagnosis. Finally, we delve into frontiers in systems integration for AI, discussing automated pipelines and evolving computing platforms that leverage distributed, decentralized and quantum techniques.

Authors

  • Nicole M Thomasian
    Warren Alpert Medical School of Brown University, Brown University, 222 Richmond Street, Providence, RI, 02906, USA. nicole_thomasian@brown.edu.
  • Ihab R Kamel
    The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, The Johns Hopkins Hospital, 1800 Orleans Street, Baltimore, MD 21287 (A.B., G.Z., I.R.K., S.L.Z., B.A.V.).
  • Harrison X Bai
    Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.