OBJECTIVE: To explore stakeholder experiences with implementing the living guideline (LG) development framework in oncology, and to identify barriers, facilitators and solutions to support its uptake and sustainability. DESIGN: An exploratory sequent...
Single-atom nanozymes (SANs) with transition metals as their core are nanomaterials characterized by atomically dispersed active sites and intrinsic enzyme-mimicking activity, exhibiting ultrahigh catalytic efficiency. As an essential trace element a...
BACKGROUND: Metastatic cancer remains one of the leading causes of cancer-related mortality worldwide. Yet, the prediction of survivability in this population remains limited by heterogeneous clinical presentations and high-dimensional molecular feat...
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Jan 6, 2026
PURPOSE: This scoping review explores how machine learning (ML) and natural language processing (NLP) are used to detect, characterize, and predict neurocognitive symptoms in cancer survivors across age groups. The review had two goals: (1) to compar...
The development of neoantigen-based cancer vaccines has emerged as a groundbreaking approach in the field of personalized oncology. Neoantigens, originating from tumor-specific somatic mutations, possess considerable immunogenic potential and are abs...
BACKGROUND: Cancer is the second leading cause of death worldwide. While significant progress has been made in early detection and treatment, metastasis remains the major cause of cancer-related morbidity and mortality. In the last decade the rate of...
The subspecialty of cardio-oncology has undergone significant growth in recent years, alongside major advances in the management of both cardiovascular disease and cancer, the leading causes of morbidity and mortality in the United States and many co...
Single-molecule detection (SMD) holds considerable promise in biomedical research. Although atomic force microscopy (AFM) provides an important technique with nanoscale resolution for SMD, its broader application is limited by labeling challenges and...
Journal of computer-aided molecular design
Dec 29, 2025
Cancer immune evasion is predominantly mediated through immune checkpoint pathways, such as the PD-1/PD-L1 axis. In this mechanism, PD-L1, which is often overexpressed on tumor cells, binds to PD-1 receptors on T cells, resulting in the inhibition of...
. Magnetic resonance imaging (MRI) guided radiotherapy requires the delineation of gross tumor volumes (GTV) in daily MRI from MRI-linacs. Specialized models have been developed for this task for certain tumors. This study investigated an alternative...
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