Robust optimization of convolutional neural networks with a uniform experiment design method: a case of phonocardiogram testing in patients with heart diseases.

Journal: BMC bioinformatics
Published Date:

Abstract

BACKGROUND: Heart sound measurement is crucial for analyzing and diagnosing patients with heart diseases. This study employed phonocardiogram signals as the input signal for heart disease analysis due to the accessibility of the respective method. This study referenced preprocessing techniques proposed by other researchers for the conversion of phonocardiogram signals into characteristic images composed using frequency subband. Image recognition was then conducted through the use of convolutional neural networks (CNNs), in order to classify the predicted of phonocardiogram signals as normal or abnormal. However, CNN requires the tuning of multiple hyperparameters, which entails an optimization problem for the hyperparameters in the model. To maximize CNN robustness, the uniform experiment design method and a science-based methodical experiment design were used to optimize CNN hyperparameters in this study.

Authors

  • Wen-Hsien Ho
    Department of Healthcare Administration and Medical Informatics, 38023Kaohsiung Medical University, Kaohsiung 807, Taiwan.
  • Tian-Hsiang Huang
    Center for Big Data Research, Kaohsiung Medical University, No. 100, Shin-Chuan 1st Road, Kaohsiung, 807, Taiwan.
  • Po-Yuan Yang
    Department of Information Engineering and Computer Science, Feng Chia University, No. 100, Wenhwa Road, Taichung, 407, Taiwan.
  • Jyh-Horng Chou
    Department of Healthcare Administration and Medical Informatics, Kaohsiung Medical University, No. 100, Shin-Chuan 1st Road, Kaohsiung, 807, Taiwan.
  • Jin-Yi Qu
    Department of Electrical Engineering, National Kaohsiung University of Science and Technology, No. 415, Chien-Kung Road, Kaohsiung, 807, Taiwan.
  • Po-Chih Chang
    Division of Thoracic Surgery, Department of Surgery, Kaohsiung Medical University Hospital, No.100, Shin-Chuan 1st Road, Kaohsiung, 807, Taiwan.
  • Fu-I Chou
    Department of Electrical Engineering, National Kaohsiung University of Science and Technology, No. 415, Chien-Kung Road, Kaohsiung, 807, Taiwan. alvis.cfi@gmail.com.
  • Jinn-Tsong Tsai
    Department of Healthcare Administration and Medical Informatics, 38023Kaohsiung Medical University, Kaohsiung 807, Taiwan.