Deep Neural Network With Consistency Regularization of Multi-Output Channels for Improved Tumor Detection and Delineation.

Journal: IEEE transactions on medical imaging
Published Date:

Abstract

Deep learning is becoming an indispensable tool for imaging applications, such as image segmentation, classification, and detection. In this work, we reformulate a standard deep learning problem into a new neural network architecture with multi-output channels, which reflects different facets of the objective, and apply the deep neural network to improve the performance of image segmentation. By adding one or more interrelated auxiliary-output channels, we impose an effective consistency regularization for the main task of pixelated classification (i.e., image segmentation). Specifically, multi-output-channel consistency regularization is realized by residual learning via additive paths that connect main-output channel and auxiliary-output channels in the network. The method is evaluated on the detection and delineation of lung and liver tumors with public data. The results clearly show that multi-output-channel consistency implemented by residual learning improves the standard deep neural network. The proposed framework is quite broad and should find widespread applications in various deep learning problems.

Authors

  • Hyunseok Seo
    Medical Physics Division in the Department of Radiation Oncology, School of Medicine, Stanford University, Stanford, CA, 94305-5847, USA.
  • Lequan Yu
  • Hongyi Ren
    Medical Physics Division in the Department of Radiation Oncology, School of Medicine, Stanford University, Stanford, CA, 94305-5847, USA.
  • Xiaomeng Li
  • Liyue Shen
    Department of Radiation Oncology, Stanford University, Stanford, California.
  • Lei Xing
    Department of Radiation Oncology, Stanford University, CA, USA.