Artificial Intelligence: Present and Future Potential for Solid Organ Transplantation.

Journal: Transplant international : official journal of the European Society for Organ Transplantation
PMID:

Abstract

Artificial intelligence (AI) refers to computer algorithms used to complete tasks that usually require human intelligence. Typical examples include complex decision-making and- image or speech analysis. AI application in healthcare is rapidly evolving and it undoubtedly holds an enormous potential for the field of solid organ transplantation. In this review, we provide an overview of AI-based approaches in solid organ transplantation. Particularly, we identified four key areas of transplantation which could be facilitated by AI: organ allocation and donor-recipient pairing, transplant oncology, real-time immunosuppression regimes, and precision transplant pathology. The potential implementations are vast-from improved allocation algorithms, smart donor-recipient matching and dynamic adaptation of immunosuppression to automated analysis of transplant pathology. We are convinced that we are at the beginning of a new digital era in transplantation, and that AI has the potential to improve graft and patient survival. This manuscript provides a glimpse into how AI innovations could shape an exciting future for the transplantation community.

Authors

  • Andrea Peloso
    Division of Transplantation, Department of Surgery, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland.
  • Beat Moeckli
    Department of General Surgery, University of Geneva Hospitals, University of Geneva, Geneva, Switzerland.
  • Vaihere Delaune
    Department of General Surgery, University of Geneva Hospitals, University of Geneva, Geneva, Switzerland.
  • Graziano Oldani
    Department of General Surgery, University of Geneva Hospitals, University of Geneva, Geneva, Switzerland.
  • Axel Andres
    Department of General Surgery, University of Geneva Hospitals, University of Geneva, Geneva, Switzerland.
  • Philippe Compagnon
    Department of Transplantation, University of Geneva Hospitals, University of Geneva, Geneva, Switzerland.