OBJECTIVE: To explore stakeholder experiences with implementing the living guideline (LG) development framework in oncology, and to identify barriers, facilitators and solutions to support its uptake and sustainability. DESIGN: An exploratory sequent...
The development of neoantigen-based cancer vaccines has emerged as a groundbreaking approach in the field of personalized oncology. Neoantigens, originating from tumor-specific somatic mutations, possess considerable immunogenic potential and are abs...
The subspecialty of cardio-oncology has undergone significant growth in recent years, alongside major advances in the management of both cardiovascular disease and cancer, the leading causes of morbidity and mortality in the United States and many co...
The aim is to present expert-agreed guidelines for the primary prevention of cardiovasculotoxicity of anticancer therapy as part of the Cardioprotection 2025 Consensus of the Russian Society of Cardiology, the Society of Heart Failure Specialists, th...
BACKGROUND: In oncology, early palliative care enhances quality of life and may increase survival; yet, because of resource limitations and overestimation of prognosis, referrals frequently happen late. Due to a shortage of specialised workers, this ...
European journal of cancer (Oxford, England : 1990)
Dec 11, 2025
INTRODUCTION: Large language models (LLMs) are utilized to answer queries in urology and oncology, yet the performance is limited due to outdated data and missing source transparency, which undermines clinical reliability and therefore adoption. MATE...
The adoption of whole genome sequencing (WGS) in clinical oncology is challenged by low data quality and increased artifacts in standard-of-care formalin-fixed paraffin-embedded (FFPE) samples. Analysis of 56 fresh frozen (FF) and FFPE matched pairs ...
Oncology clinical trials play a pivotal role in the development of new therapeutic options; however, their implementation remains an extremely costly and time-consuming process. Artificial intelligence can open new horizons in the design and conduct ...
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