Renal Function Estimates and Dosing of Direct Oral Anticoagulants in Stroke Patients with Atrial Fibrillation: An Observational Study.
Journal:
Acta neurologica Taiwanica
PMID:
31304571
Abstract
PURPOSE: Appropriate dosing of direct oral anticoagulants (DOACs) requires consideration of renal function. Discordance between commonly used estimated glomerular filtration rate (eGFR) and creatinine clearance (CrCl) might affect the dosing appropriateness in stroke patients with atrial fibrillation (AF). We aimed to explore the effect of renal function estimates on the dosing patterns in a real-world setting.