Segmentation and Classification of Glaucoma Using U-Net with Deep Learning Model.

Journal: Journal of healthcare engineering
Published Date:

Abstract

Glaucoma is the second most common cause for blindness around the world and the third most common in Europe and the USA. Around 78 million people are presently living with glaucoma (2020). It is expected that 111.8 million people will have glaucoma by the year 2040. 90% of glaucoma is undetected in developing nations. It is essential to develop a glaucoma detection system for early diagnosis. In this research, early prediction of glaucoma using deep learning technique is proposed. In this proposed deep learning model, the ORIGA dataset is used for the evaluation of glaucoma images. The U-Net architecture based on deep learning algorithm is implemented for optic cup segmentation and a pretrained transfer learning model; DenseNet-201 is used for feature extraction along with deep convolution neural network (DCNN). The DCNN approach is used for the classification, where the final results will be representing whether the glaucoma infected or not. The primary objective of this research is to detect the glaucoma using the retinal fundus images, which can be useful to determine if the patient was affected by glaucoma or not. The result of this model can be positive or negative based on the outcome detected as infected by glaucoma or not. The model is evaluated using parameters such as accuracy, precision, recall, specificity, and F-measure. Also, a comparative analysis is conducted for the validation of the model proposed. The output is compared to other current deep learning models used for CNN classification, such as VGG-19, Inception ResNet, ResNet 152v2, and DenseNet-169. The proposed model achieved 98.82% accuracy in training and 96.90% in testing. Overall, the performance of the proposed model is better in all the analysis.

Authors

  • M B Sudhan
    Department of Artificial Intelligence and Machine Learning, MVJ College of Engineering, Bangalore, Karnataka, India.
  • M Sinthuja
    Department of Information Science and Engineering, M. S. Ramaiah Institute of Technology, Bangalore, Karnataka, India.
  • S Pravinth Raja
    Department of Computer Science & Engineering, Presidency University, Bangalore, Karnataka, India.
  • J Amutharaj
    Department of Information Science and Engineering, RajaRajeswari College of Engineering, Mysore Road, Bangalore, Karnataka, India.
  • G Charlyn Pushpa Latha
    Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences (Deemed to be University), Chennai, Tamilnadu, India.
  • S Sheeba Rachel
    Department of Information Technology, Sri Sairam Engineering College (Autonomous), Chennai, Tamilnadu, India.
  • T Anitha
    Department of Computer Science and Engineering, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences (Deemed to be University), Chennai, Tamilnadu, India.
  • T Rajendran
    Makeit Technologies, Coimbatore, Tamilnadu, India.
  • Yosef Asrat Waji
    Department of Chemical Engineering, College of Biological and Chemical Engineering Addis Ababa Science and Technology University, Addis Ababa, Ethiopia.