AIMC Topic: Optic Disk

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DB-SegNet: optimized framework for glaucoma detection and optic structure segmentation from retinal fundus images.

Scientific reports
Glaucoma remains one of the primary causes of irreversible blindness, characterized by gradual damage to the optic nerve, which often goes undetected until advanced stages. Accurate and early diagnosis depends heavily on precise segmentation of the o...

Optic disc morphometrics as a potential ocular biomarker for depression: evidence from two cross-sectional cohort studies.

Translational psychiatry
Depression, which is increasingly prevalent among older adults, has traditionally been diagnosed through symptom-based questionnaires. However, emerging evidence suggests that retinal changes could serve as objective biomarkers for depression. In thi...

Differentiation of optic disc edema and pseudopapilledema with deep learning on near-infrared reflectance images.

BMC ophthalmology
BACKGROUND: This study aimed to develop an artificial intelligence-based deep learning (DL) algorithm using near-infrared reflectance (NIR) images to differentiate between optic disc edema and pseudopapilledema, and to evaluate the diagnostic perform...

Comparison of the number of peripapillary perforating scleral vessels between glaucomatous eyes and healthy eyes.

Scientific reports
This study aimed to compare the number of peripapillary perforating scleral vessels (PPSVs) between eyes with and without glaucoma. A retrospective case-control analysis was performed on patients with glaucoma and control participants who underwent s...

Analysis of 2-dimensional regional differences in the peripapillary scleral fibroblast cytoskeleton of normotensive and hypertensive mouse eyes.

Scientific reports
These studies aimed to study the mechanisms of glaucomatous peripapillary scleral (PPS) remodeling by investigating IOP-induced changes in fibroblast actin-collagen alignment and nuclear morphology in mouse PPS. Cryosections from the optic nerve head...

Advances in risk prediction models for Glaucoma: An updated narrative review.

Experimental eye research
Glaucoma is a leading cause of irreversible blindness and is characterized by optic nerve atrophy and progressive visual field loss. Risk prediction models are crucial for early screening and personalized treatment by identifying high-risk individual...

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International ophthalmology
UNLABELLED: Early detection of glaucoma represents a vital factor in securing vision while the disease retains its position as one of the central causes of blindness worldwide. The current glaucoma screening strategies with expert interpretation depe...

Enhanced glaucoma classification through advanced segmentation by integrating cup-to-disc ratio and neuro-retinal rim features.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Glaucoma is a progressive eye condition caused by high intraocular fluid pressure, damaging the optic nerve, leading to gradual, irreversible vision loss, often without noticeable symptoms. Subtle signs like mild eye redness, slightly blurred vision,...

Optimized glaucoma detection using HCCNN with PSO-driven hyperparameter tuning.

Biomedical physics & engineering express
. This study is focused on creating an effective glaucoma detection system employing a Hybrid Centric Convolutional Neural Network (HCCNN) model. By using Particle Swarm Optimization (PSO), classification accuracy is increased and computing complexit...

Sharper insights: Adaptive ellipse-template for robust fovea localization in challenging retinal landscapes.

Computers in biology and medicine
Automated identification of retinal landmarks, particularly the fovea is crucial for diagnosing diabetic retinopathy and other ocular diseases. But accurate identification is challenging due to varying contrast, color irregularities, anatomical struc...