Deep Learning Approach for Automatic Microaneurysms Detection.

Journal: Sensors (Basel, Switzerland)
Published Date:

Abstract

In diabetic retinopathy (DR), the early signs that may lead the eyesight towards complete vision loss are considered as microaneurysms (MAs). The shape of these MAs is almost circular, and they have a darkish color and are tiny in size, which means they may be missed by manual analysis of ophthalmologists. In this case, accurate early detection of microaneurysms is helpful to cure DR before non-reversible blindness. In the proposed method, early detection of MAs is performed using a hybrid feature embedding approach of pre-trained CNN models, named as VGG-19 and Inception-v3. The performance of the proposed approach was evaluated using publicly available datasets, namely "E-Ophtha" and "DIARETDB1", and achieved 96% and 94% classification accuracy, respectively. Furthermore, the developed approach outperformed the state-of-the-art approaches in terms of sensitivity and specificity for microaneurysms detection.

Authors

  • Muhammad Mateen
    Department of Computer Science, Air University Multan Campus, Multan 60000, Pakistan.
  • Tauqeer Safdar Malik
    Department of Computer Science, Air University Multan Campus, Multan 60000, Pakistan.
  • Shaukat Hayat
    Department of Computer Science, Iqra National University, Peshawar 25000, Pakistan.
  • Musab Hameed
    Department of Electrical & Computer Engineering, Sahiwal Campus, COMSATS University Islamabad, Sahiwal 57000, Pakistan.
  • Song Sun
    School of Big Data & Software Engineering, Chongqing University, Chongqing 401331, China.
  • Junhao Wen
    Laboratory of AI and Biomedical Science (LABS), Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of USC, University of Southern California, Los Angeles, California, USA.