Development and validation of a radiopathomics model to predict pathological complete response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer: a multicentre observational study.

Abstract

Authors

• Lili Feng
  Department of Radiation Oncology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China; Guangdong Institute of Gastroenterology, Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, Guangzhou, China.
• Zhenyu Liu
  School of Electronic Information, Hangzhou Dianzi University, Hangzhou 310018, China.
• Chaofeng Li
  State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, 510060, P. R. China.
• Zhenhui Li
  College of Information Sciences and Technology, Pennsylvania State University.
• Xiaoying Lou
  Department of Pathology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
• Lizhi Shao
  CAS Key Laboratory of Molecular Imaging, Institute of Automation, Chinese Academy of Sciences, Beijing, China; School of Computer Science and Engineering, Southeast University, Nanjing, China.
• Yunlong Wang
  Department of Radiation Oncology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China; Guangdong Institute of Gastroenterology, Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, Guangzhou, China.
• Yan Huang
  Department of Neurology, University of Texas Health Science Center at Houston, Houston, TX.
• Haiyang Chen
• Xiaolin Pang
  Department of Radiation Oncology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
• Shuai Liu
  Graduate School of Chinese Academy of Traditional Chinese Medicine, Beijing, China.
• Fang He
  Department of Applied Mathematics, The Hong Kong Polytechnic University, Hong Kong.
• Jian Zheng
  Biospheric Assessment for Waste Disposal Team, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, 4-9-1 Anagawa, Inage, Chiba 263-8555, Japan; Fukushima Project Headquarters, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, 4-9-1 Anagawa, Inage, Chiba 263-8555, Japan. Electronic address: zheng.jian@qst.go.jp.
• Xiaochun Meng
  Department of Radiology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510655, China.
• Peiyi Xie
  Department of Radiology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510655, China.
• Guanyu Yang
  Laboratory of Image Science and Technology, School of Computer Science and Engineering, Southeast University, Nanjing, China; Key Laboratory of Computer Network and Information Integration (Southeast University), Ministry of Education, Nanjing, China; Centre de Recherche en Information Biomedicale Sino-Francais (LIA CRIBs), Rennes, France.
• Yi Ding
  Clinical and Research Center of AIDS, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
• Mingbiao Wei
  Department of Radiation Oncology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China; Guangdong Institute of Gastroenterology, Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, Guangzhou, China.
• Jingping Yun
  Department of Pathology, Sun Yat-sen University Cancer Center, Guangzhou, China.
• Mien-Chie Hung
  Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Graduate Institute of Biomedical Sciences and Research Centers for Cancer Biology and Molecular Medicine, China Medical University, Taichung, Taiwan; Department of Biotechnology, Asia University, Taichung, Taiwan.
• Weihua Zhou
  School of Computing, University of Southern Mississippi, Hattiesburg, MS, United States of America.
• Daniel R Wahl
  Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA.
• Ping Lan
  Department of Colorectal Surgery, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China; Guangdong Institute of Gastroenterology, Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, Guangzhou, China.
• Jie Tian
  CAS Key Laboratory of Molecular Imaging, Institute of Automation, Chinese Academy of Sciences, Beijing 100190, China.
• Xiangbo Wan
  Department of Radiation Oncology, The Sixth Affiliated Hospital of Sun Yat-sen University, China.

Keywords

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