Morphological components detection for super-depth-of-field bio-micrograph based on deep learning.

Journal: Microscopy (Oxford, England)
Published Date:

Abstract

Accompanied with the clinical routine examination demand increase sharply, the efficiency and accuracy are the first priority. However, automatic classification and localization of cells in microscopic images in super depth of Field (SDoF) system remains great challenges. In this paper, we advance an object detection algorithm for cells in the SDoF micrograph based on Retinanet model. Compared with the current mainstream algorithm, the mean average precision (mAP) index is significantly improved. In the experiment of leucorrhea samples and fecal samples, mAP indexes are 83.1% and 88.1%, respectively, with an average increase of 10%. The object detection model proposed in this paper can be applied to feces and leucorrhea detection equipment, and significantly improve the detection efficiency and accuracy.

Authors

  • Xiaohui Du
  • Xiangzhou Wang
    School of Optoelectronic Information, University of Electronic Science and Technology of China, Chengdu, 610054, China.
  • Fan Xu
    Department of Public Health, Chengdu Medical College, Sichuan, China.
  • Jing Zhang
    MOEMIL Laboratory, School of Optoelectronic Information, University of Electronic Science and Technology of China, Chengdu, China.
  • Yibo Huo
  • Guangmin Ni
  • Ruqian Hao
  • Juanxiu Liu
  • Lin Liu
    Institute of Natural Sciences, MOE-LSC, School of Mathematical Sciences, CMA-Shanghai, SJTU-Yale Joint Center for Biostatistics and Data Science, Shanghai Jiao Tong University; Shanghai Artificial Intelligence Laboratory.