Image Quality Assessment (IQA) plays a critical role in image-based decision-making systems, especially in domains requiring high diagnostic precision. Effective feature information is a prerequisite for the high performance of machine learning metho...
Super-resolution microscopy, particularly localization-based methods, necessitates careful balancing of optical complexity, computational demands, and user accessibility. Conventional strategies typically adopt either deterministic or learning-based ...
Plasmodium vivax is a malaria parasite with a broad geographic distribution worldwide. The unique biological characteristics of P. vivax, such as early gametocytogenesis and its latent hypnozoite stage, make it more difficult to control compared to P...
Traditional hematoxylin and eosin staining in formalin-fixed paraffin-embedded sections, while essential for diagnostic pathology, is time-consuming, labor intensive, and prone to artifacts that can obscure critical histological details. Label-free u...
is a Gram-negative bacterial pathogen and causative agent of bacillary dysentery. is closely related to but harbours a virulence plasmid that encodes a type III secretion system (T3SS) required for host cell invasion. Widely recognised as a paradi...
Infrared spectroscopy of macroscopic samples can be calibrated against reference analysis, such as lipid profiles acquired by gas chromatography, and serve as a fast, low-cost, quantitative analytical method. Calibration of infrared microspectroscopi...
Real-time monitoring of phytoplankton in freshwater systems is critical for early detection of harmful algal blooms (HABs) to enable efficient response by water management agencies. This manuscript presents an image processing pipeline developed to a...
Cellular and molecular life sciences : CMLS
Aug 29, 2025
The 3D organization of the genome plays a critical role in regulating gene expression, maintaining cellular identity, and mediating responses to environmental cues. Advances in super-resolution microscopy and genomic technologies have enabled unprece...
Insufficient coverage of cervical cytology screening in resource-limited areas remains a major bottleneck for women's health, as traditional centralized methods require significant investment and many qualified pathologists. Using consumer-grade elec...
Accurate interpretation of human epidermal growth factor receptor 2 (HER2) immunohistochemistry (IHC) scores 0 and 1+ is crucial for treating HER2-low breast cancer patients with antibody-drug conjugates. To improve diagnostic precision, we developed...
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