Rethinking the neighborhood information for deep learning-based optical coherence tomography angiography.

Journal: Medical physics
Published Date:

Abstract

PURPOSE: Optical coherence tomography angiography (OCTA) is a premium imaging modality for noninvasive microvasculature studies. Deep learning networks have achieved promising results in the OCTA reconstruction task, benefiting from their powerful modeling capability. However, two limitations exist in the current deep learning-based OCTA reconstruction methods: (a) the angiogram information extraction is only limited to the locally consecutive B-scans; and (b) all reconstruction models are confined to the 2D convolutional network architectures, lacking effective temporal modeling. As a result, the valuable neighborhood information and inherent temporal characteristics of OCTA are not fully utilized. In this paper, we designed a neighborhood information-fused Pseudo-3D U-Net (NI-P3D-U) for OCTA reconstruction.

Authors

  • Zhe Jiang
    Department of Biomedical Engineering, College of Engineering, Peking University, Beijing, China.
  • Zhiyu Huang
    Department of Biomedical Engineering, College of Engineering, Peking University, Beijing, China.
  • Yunfei You
    Department of Biomedical Engineering, College of Engineering, Peking University, Beijing, China.
  • Mufeng Geng
  • Xiangxi Meng
    Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Nuclear Medicine, Peking University Cancer Hospital & Institute, Beijing, China.
  • Bin Qiu
    MOE Key Laboratory for Analytical Science of Food Safety and Biology, Fujian Provincial Key Laboratory of Analysis and Detection for Food Safety, College of Chemistry, Fuzhou University, Fuzhou, Fujian 350116, China.
  • Lei Zhu
    School of Civil and Hydraulic Engineering, Ningxia University, Yinchuan, China.
  • Mengdi Gao
  • Jing Wang
    Endoscopy Center, Peking University Cancer Hospital and Institute, Beijing, China.
  • Chuanqing Zhou
    Institute of Biomedical Engineering, Shenzhen Bay Laboratory, Shenzhen, China.
  • Qiushi Ren
    Department of Biomedical Engineering, Peking University, 100871, Beijing, China.
  • Yanye Lu
    Pattern Recognition Lab, Friedrich-Alexander-Universität Erlangen-Nürnberg, Martensstr. 3, 91058, Erlangen, Germany. yanye.lu@fau.de.