Automated diagnosis of age-related macular degeneration using multi-modal vertical plane feature fusion via deep learning.

Journal: Medical physics
Published Date:

Abstract

PURPOSE: To develop a computer-aided diagnostic (CADx) system of age-related macular degeneration (AMD) through feature fusion between infrared reflectance (IR) and optical coherence tomography (OCT) modalities in order to explore the superiority of multi-modality CADx system and the optimal feature fusion patterns between multi-modality inputs.

Authors

  • Menglu Chen
    Department of Ophthalmology, College of Medicine, The Second Affiliated Hospital of Zhejiang University, Hangzhou, China.
  • Kai Jin
    Eye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
  • Yan Yan
    Department of Biomedical Engineering, Wayne State University, Detroit, Michigan, USA.
  • Xindi Liu
    Department of Ophthalmology, College of Medicine, The Second Affiliated Hospital of Zhejiang University, Hangzhou, China.
  • Xiaoling Huang
    Department of Ophthalmology, The Second Affiliated Hospital of Zhejiang University, College of Medicine, Hangzhou, 310009, China.
  • Zhiyuan Gao
    Department of Ophthalmology, The Second Affiliated Hospital of Zhejiang University, College of Medicine, Hangzhou, Zhejiang, China.
  • Yao Wang
    Department of Gastrointestinal Surgery, Zhongshan People's Hospital, Zhongshan, Guangdong, China.
  • Shuai Wang
    Department of Intensive Care Unit, China-Japan Union Hospital of Jilin University, Changchun, China.
  • Juan Ye
    Eye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.