Artificial intelligence for histological subtype classification of breast cancer: combining multi-scale feature maps and the recurrent attention model.

Journal: Histopathology
Published Date:

Abstract

AIMS: The aim of this study was to apply a two-stage deep model combining multi-scale feature maps and the recurrent attention model (RAM) to assist with the pathological diagnosis of breast cancer histological subtypes by the use of whole slide images (WSIs).

Authors

  • Junjie Li
    Department of Emergency, Xijing Hospital, Fourth Military Medical University, No. 127 West Changle Road, Xi'an, China.
  • Weiming Mi
    Department of Automation, School of Information Science and Technology, Tsinghua University, Beijing, China.
  • Yucheng Guo
    Qingdao Jimo District Administration Examination and Approval Service Bureau of Shandong Province, Qingdao, Shandong 266200, China.
  • Xinyu Ren
    Department of Pathology, State Key Laboratory of Complex Severe and Rare Diseases, Molecular Pathology Research Centre, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.
  • Hao Fu
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, P. R. China.
  • Tao Zhang
    Department of Traumatology, Chongqing Emergency Medical Center, Chongqing University Central Hospital, School of Medicine, Chongqing University, Chongqing, 40044, People's Republic of China.
  • Hao Zou
    Tsimage Medical Technology, Yihai Centre, Yantian District, Shenzhen, China.
  • Zhiyong Liang
    Department of Pathology, State Key Laboratory of Complex Severe and Rare Diseases, Molecular Pathology Research Centre, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.