Clinical target segmentation using a novel deep neural network: double attention Res-U-Net.

Journal: Scientific reports
Published Date:

Abstract

We introduced Double Attention Res-U-Net architecture to address medical image segmentation problem in different medical imaging system. Accurate medical image segmentation suffers from some challenges including, difficulty of different interest object modeling, presence of noise, and signal dropout throughout the measurement. The base line image segmentation approaches are not sufficient for complex target segmentation throughout the various medical image types. To overcome the issues, a novel U-Net-based model proposed that consists of two consecutive networks with five and four encoding and decoding levels respectively. In each of networks, there are four residual blocks between the encoder-decoder path and skip connections that help the networks to tackle the vanishing gradient problem, followed by the multi-scale attention gates to generate richer contextual information. To evaluate our architecture, we investigated three distinct data-sets, (i.e., CVC-ClinicDB dataset, Multi-site MRI dataset, and a collected ultrasound dataset). The proposed algorithm achieved Dice and Jaccard coefficients of 95.79%, 91.62%, respectively for CRL, and 93.84% and 89.08% for fetal foot segmentation. Moreover, the proposed model outperformed the state-of-the-art U-Net based model on the external CVC-ClinicDB, and multi-site MRI datasets with Dice and Jaccard coefficients of 83%, 75.31% for CVC-ClinicDB, and 92.07% and 87.14% for multi-site MRI dataset, respectively.

Authors

  • Vahid Ashkani Chenarlogh
    Research and Development Department, Med Fanavarn Plus Co., Karaj, Iran.
  • Ali Shabanzadeh
    Research and Development Department, Med Fanavarn Plus Co., Karaj, Iran. Electronic address: shabanzadeh.ali@gmail.com.
  • Mostafa Ghelich Oghli
    Research and Development Department, Med Fanavarn Plus Co., Karaj, Iran; Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium. Electronic address: m.g31_mesu@yahoo.com.
  • Nasim Sirjani
    Research and Development Department, Med Fanavarn Plus Co., Karaj, Iran.
  • Sahar Farzin Moghadam
    Research and Development Department, Med Fanavaran Plus Co., Karaj, Iran.
  • Ardavan Akhavan
    Research and Development Department, Med Fanavarn Plus Co., Karaj, Iran.
  • Hossein Arabi
    Division of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, CH-1211, Geneva 4, Switzerland.
  • Isaac Shiri
    Biomedical and Health Informatics, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran.
  • Zahra Shabanzadeh
    School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Morteza Sanei Taheri
    R Department of Radiology, Shohada-e-Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Mohammad Kazem Tarzamni
    Department of Radiology, Imam Reza Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.