Automatic recognition of micronucleus by combining attention mechanism and AlexNet.

Journal: BMC medical informatics and decision making
Published Date:

Abstract

BACKGROUND: Micronucleus (MN) is an abnormal fragment in a human cell caused by disorders in the mechanism regulating chromosome segregation. It can be used as a biomarker for genotoxicity, tumor risk, and tumor malignancy. The in vitro micronucleus assay is a commonly used method to detect micronucleus. However, it is time-consuming and the visual scoring can be inconsistent.

Authors

  • Weiyi Wei
    College of Computer Science and Engineering, Northwest Normal University, Lanzhou, China.
  • Hong Tao
    College of Computer Science and Engineering, Northwest Normal University, Lanzhou, China. 2020222065@nwnu.edu.cn.
  • Wenxia Chen
    Department of Otolaryngology-Head and Neck Surgery, Children's Hospital of Fudan University, Shanghai 201102, China.
  • Xiaoqin Wu
    Radiology Department, Gansu Provincial Center For Disease Control And Prevention, Lanzhou, China.