SDNN-PPI: self-attention with deep neural network effect on protein-protein interaction prediction.

Journal: BMC genomics
Published Date: Jun 27, 2022

Abstract

BACKGROUND: Protein-protein interactions (PPIs) dominate intracellular molecules to perform a series of tasks such as transcriptional regulation, information transduction, and drug signalling. The traditional wet experiment method to obtain PPIs information is costly and time-consuming.

Authors

  • Xue Li
    Department of Clinical Research Center, Dazhou Central Hospital, Dazhou 635000, China.
  • Peifu Han
    College of Computer Science and technology, China University of Petroleum (East China), Qingdao, China.
  • Gan Wang
    College of Computer Science and Technology, China University of Petroleum, Qingdao 266580, China.
  • Wenqi Chen
    College of Computer Science and technology, China University of Petroleum (East China), Qingdao, China.
  • Shuang Wang
    Engineering Technology Research Center of Shanxi Province for Opto-Electric Information and Instrument, Taiyuan 030051, China. S1507038@st.nuc.edu.cn.
  • Tao Song
    Department of Cleft Lip and Palate, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing.

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