Survival prediction models: an introduction to discrete-time modeling.

Journal: BMC medical research methodology
PMID:

Abstract

BACKGROUND: Prediction models for time-to-event outcomes are commonly used in biomedical research to obtain subject-specific probabilities that aid in making important clinical care decisions. There are several regression and machine learning methods for building these models that have been designed or modified to account for the censoring that occurs in time-to-event data. Discrete-time survival models, which have often been overlooked in the literature, provide an alternative approach for predictive modeling in the presence of censoring with limited loss in predictive accuracy. These models can take advantage of the range of nonparametric machine learning classification algorithms and their available software to predict survival outcomes.

Authors

  • Krithika Suresh
    Department of Biostatistics and Informatics, University of Colorado Anschutz Medical Campus, Aurora, 80045, Colorado, USA. krithika.suresh@cuanschutz.edu.
  • Cameron Severn
    Department of Biostatistics and Informatics, University of Colorado, Aurora, CO 80045, USA.
  • Debashis Ghosh
    Department of Biostatistics and Informatics, Colorado School of Public Health, Aurora, USA.