Enhancing classification of cells procured from bone marrow aspirate smears using generative adversarial networks and sequential convolutional neural network.
Journal:
Computer methods and programs in biomedicine
PMID:
35878483
Abstract
BACKGROUND AND OBJECTIVE: Leukemia represents 30% of all pediatric cancers and is considered the most common malignancy affecting adults and children. Cell differential count obtained from bone marrow aspirate smears is crucial for diagnosing hematologic diseases. Classification of these cell types is an essential task towards analyzing the disease, but it is time-consuming and requires intensive manual intervention. While machine learning has shown excellent outcomes in automating medical diagnosis, it needs ample data to build an efficient model for real-world tasks. This paper aims to generate synthetic data to enhance the classification accuracy of cells obtained from bone marrow aspirate smears.