An artificial intelligence model correlated with morphological and genetic features of blastocyst quality improves ranking of viable embryos.

Journal: Reproductive biomedicine online
Published Date: Dec 1, 2022

Abstract

RESEARCH QUESTION: Can better methods be developed to evaluate the performance and characteristics of an artificial intelligence model for evaluating the likelihood of clinical pregnancy based on analysis of day-5 blastocyst-stage embryos, such that performance evaluation more closely reflects clinical use in IVF procedures, and correlations with known features of embryo quality are identified?

Authors

  • Sonya M Diakiw
    Life Whisperer Diagnostics (a subsidiary of Presagen), San Francisco CA 94404, USA, and Adelaide SA 5000, Australia. Electronic address: sonya@lifewhisperer.com.
  • Jonathan M M Hall
    Life Whisperer Diagnostics (a subsidiary of Presagen), San Francisco CA 94404, USA, and Adelaide SA 5000, Australia; Australian Research Council Centre of Excellence for Nanoscale BioPhotonics, Adelaide SA 5000, Australia; School of Physical Sciences, The University of Adelaide, Adelaide SA 5000, Australia.
  • Matthew VerMilyea
    Ovation Fertility, Austin TX 78731, USA; Texas Fertility Center, Austin TX 78731, USA.
  • Adelle Y X Lim
    Alpha IVF and Women's Specialists, Petaling Jaya Selangor 47810, Malaysia.
  • Wiwat Quangkananurug
    Safe Fertility, Lumpini Bangkok 10330, Thailand.
  • Sujin Chanchamroen
    Safe Fertility, Lumpini Bangkok 10330, Thailand.
  • Brandon Bankowski
    ORM Fertility, Portland OR 97205, USA.
  • Rebecca Stones
    ORM Fertility, Portland OR 97205, USA.
  • Ashleigh Storr
    Flinders Fertility, Glenelg SA 5045, Australia.
  • Andrew Miller
    Ovation Fertility, Austin TX 78731, USA.
  • Glen Adaniya
    Midwest Fertility Specialists, Carmel IN 46032, USA.
  • RaeAnne van Tol
    Midwest Fertility Specialists, Carmel IN 46032, USA.
  • Roberta Hanson
    Ovation Fertility, San Antonio TX 78258, USA.
  • Jon Aizpurua
    Life Whisperer Diagnostics (a subsidiary of Presagen), San Francisco CA 94404, USA, and Adelaide SA 5000, Australia.
  • Lydia Giardini
    IVF-Spain, Alicante 03540, Spain.
  • Adrian Johnston
    Life Whisperer Diagnostics (a subsidiary of Presagen), San Francisco CA 94404, USA, and Adelaide SA 5000, Australia.
  • Tuc Van Nguyen
    Life Whisperer Diagnostics (a subsidiary of Presagen), San Francisco CA 94404, USA, and Adelaide SA 5000, Australia.
  • Milad A Dakka
    Life Whisperer Diagnostics (a subsidiary of Presagen), San Francisco CA 94404, USA, and Adelaide SA 5000, Australia.
  • Don Perugini
    Life Whisperer Diagnostics (a subsidiary of Presagen), San Francisco CA 94404, USA, and Adelaide SA 5000, Australia.
  • Michelle Perugini
    Life Whisperer Diagnostics (a subsidiary of Presagen), San Francisco CA 94404, USA, and Adelaide SA 5000, Australia; Adelaide Medical School, The University of Adelaide, Adelaide SA 5000, Australia.

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