Visualization deep learning model for automatic arrhythmias classification.

Journal: Physiological measurement
Published Date:

Abstract

With the improvement of living standards, heart disease has become one of the common diseases that threaten human health. Electrocardiography (ECG) is an effective way of diagnosing cardiovascular diseases. With the rapid growth of ECG examinations and the shortage of cardiologists, accurate and automatic arrhythmias classification has become a research hotspot. The main purpose of this paper is to improve accuracy in detecting abnormal ECG patterns.A hybrid 1D Resnet-GRU method, consisting of the Resnet and gated recurrent unit (GRU) modules, is proposed to implement classification of arrhythmias from 12-lead ECG recordings. In addition, the focal Loss function is used to solve the problem of unbalanced datasets. Based on the proposed 1D Resnet-GRU model, we use class-discriminative visualization to improve interpretability and transparency as an additional step. In this paper, the Grad-CAM++ mechanism has been employed to the trained network model and generate thermal images superimposed on raw signals to explore underlying explanations of various ECG segments.The experimental results show that the proposed method can achieve a high score of 0.821 (F1-score) in classifying 9 kinds of arrythmias, and Grad-CAM++ not only provides insight into the predictive power of the model, but is also consistent with the diagnostic approach of the arrhythmia classification.The proposed method can effectively select and integrate ECG features to achieve the goal of end-to-end arrhythmia classification by using 12-lead ECG signals, which can serve a promising and useful way for automatic arrhythmia classification, and can provide an explainable deep leaning model for clinical diagnosis.

Authors

  • Mingfeng Jiang
    School of Information Science and Technology, Zhejiang Sci-Tech University, Hangzhou 310018, People's Republic of China.
  • Yujie Qiu
    School of Information Science and Technology, Zhejiang Sci-Tech University, Hangzhou 310018, People's Republic of China.
  • Wei Zhang
    The First Affiliated Hospital of Nanchang University, Nanchang, China.
  • Jucheng Zhang
    Department of Clinical Engineering, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310019, People's Republic of China.
  • Zhefeng Wang
    Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, No. 2 Anzhen Road, Chaoyang District, Beijing 100029, People's Republic of China.
  • Wei Ke
    Huangshi Public Security Bureau, Huangshi 435000, China.
  • Yongquan Wu
    Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, No. 2 Anzhen Road, Chaoyang District, Beijing 100029, People's Republic of China.
  • Zhikang Wang
    Department of Clinical Engineering, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310019, People's Republic of China.